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Product details

Recombinant BCL6 Monoclonal Antibody

Catalog number AN301444L-01

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Price for AN301444L-01

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Size / count 50 µL

Specifications

Catalog number
AN301444L-01
Size / count
50 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
Transcriptional repressor mainly required for germinal center (GC) formation and antibody affinity maturation which has different mechanisms of action specific to the lineage and biological functions. In response to genotoxic stress, controls cell cycle arrest in GC B-cells in both p53/TP53-dependedent and -independent manners. Besides, also controls neurogenesis through the alteration of the composition of NOTCH-dependent transcriptional complexes at selective NOTCH targets, such as HES5, including the recruitment of the deacetylase SIRT1 and resulting in an epigenetic silencing leading to neuronal differentiation.
Abbreviation
BCL6
UniProt
P41182
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant human BCL6 fragment
Target
ZNF; LAZ; ZBTB; BCL; BCL6; BCL5; BCL6A; LAZ3; ZBTB27; ZNF51
Clonality
Monoclonal, Recombinant
Clone
A139
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Epigenetics and Nuclear Signaling; Cancer
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:1000-1:5000; IHC 1:100-1:500
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
79 kDa
Observed Molecular Weight
78 kDa
Isotype
IgG, κ

Frequently Asked Questions

What is the catalog number for Recombinant BCL6 Monoclonal Antibody?

The catalog number for Recombinant BCL6 Monoclonal Antibody is AN301444L.

What sizes are available for Recombinant BCL6 Monoclonal Antibody?

Recombinant BCL6 Monoclonal Antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does Recombinant BCL6 Monoclonal Antibody come in?

Recombinant BCL6 Monoclonal Antibody is available in 2 different pack sizes.

Is Recombinant BCL6 Monoclonal Antibody in stock?

Recombinant BCL6 Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant BCL6 Monoclonal Antibody?

Recombinant BCL6 Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Recombinant BCL6 Monoclonal Antibody?

Estimated delivery time for Recombinant BCL6 Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant BCL6 Monoclonal Antibody?

The safety data sheet for Recombinant BCL6 Monoclonal Antibody is available here: https://789.bio/eb/hdxRwNO9.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

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