Recombinant CD3G Monoclonal Antibody — image 1 of 3

Product details

Recombinant CD3G Monoclonal Antibody

Catalog number AN301477L-01

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Price for AN301477L-01

Size / count 50 µL

Specifications

Catalog number: AN301477L-01
Size / count: 50 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of downstream signaling pathways. In addition to this role of signal transduction in T-cell activation, CD3G plays an essential role in the dynamic regulation of TCR expression at the cell surface. Indeed, constitutive TCR cycling is dependent on the di-leucine-based (diL) receptor-sorting motif present in CD3G.
Abbreviation: CD3G
UniProt: P09693
Host: Rabbit
Reactivity: Human
Immunogen: Recombinant human CD3G fragment
Target: T3G; CD3G; T3; CD_antigen: CD3g; CD3g molecule; CD3-GAMMA; IMD17; T-cell receptor T3 gamma chain; T-cell surface glycoprotein CD3 gamma chain
Clonality: Monoclonal, Recombinant
Clone: A172
Conjugation: Unconjugated
Applications: WB; IHC; IF; IP
Field of Research: Immunology; Stem Cells
Purification: Protein A purified
Concentration: 1 mg/mL
Dilution: WB 1:500-1:1000; IHC 1:500-1:2000; IF 1:50; IP 1:50
Buffer: PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions: Ice bag
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 20 kDa
Observed Molecular Weight: 18-28 kDa
Isotype: IgG, κ

Frequently Asked Questions

What is the catalog number for Recombinant CD3G Monoclonal Antibody?

The catalog number for Recombinant CD3G Monoclonal Antibody is AN301477L.

What sizes are available for Recombinant CD3G Monoclonal Antibody?

Recombinant CD3G Monoclonal Antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does Recombinant CD3G Monoclonal Antibody come in?

Recombinant CD3G Monoclonal Antibody is available in 2 different pack sizes.

Is Recombinant CD3G Monoclonal Antibody in stock?

Recombinant CD3G Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant CD3G Monoclonal Antibody?

Recombinant CD3G Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Recombinant CD3G Monoclonal Antibody?

Estimated delivery time for Recombinant CD3G Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant CD3G Monoclonal Antibody?

The safety data sheet for Recombinant CD3G Monoclonal Antibody is available here: https://789.bio/eb/7LxW8tUN.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.