Recombinant Cleaved PARP1 p25 Monoclonal Antibody

Specifications

Catalog number

AN301494L-01

Size / count

50 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

Poly-ADP-ribosyltransferase that mediates poly-ADP-ribosylation of proteins and plays a key role in DNA repair. Mainly mediates glutamate and aspartate ADP-ribosylation of target proteins: the ADP-D-ribosyl group of NAD+ is transferred to the acceptor carboxyl group of glutamate and aspartate residues and further ADP-ribosyl groups are transferred to the 2'-position of the terminal adenosine moiety, building up a polymer with an average chain length of 20-30 units.

Abbreviation

Cleaved PARP1 p25

UniProt

P09874

Host

Rabbit

Reactivity

Human; Mouse

Immunogen

Recombinant human Cleaved PARP1 p25 fragment

Target

SCA; ARTD; Poly[ADP-ribose] synthase; Poly ADP ribose polymerase; poly (ADP-ribose) polymerase; Poly [ADP-ribose] polymerase; NAD (+) ADP-ribosyltransferase; ADP-ribosyltransferase diphtheria toxin-like; pADPRT; ADPRT; ADPRT 1; ADPRT1; ARTD1; PARP; PARP-1; PPOL; pADPRT-1; PARP1; Cleaved PARP; ADP-ribosyltransferase diphtheria toxin-like 1; APOPAIN; NAD (+) ADP-ribosyltransferase 1; Poly [ADP-ribose] polymerase 1; Poly ADP ribose polymerase 1; poly (ADP-ribose) polymerase 1; Poly[ADP-ribose] synthase 1; SCA1; ADPRT; ADPRT 1; ADPRT1; ARTD1; pADPRT-1; PARP; PARP-1; poly (ADP-ribose) polymerase 1; PPOL

Clonality

Monoclonal, Recombinant

Clone

A189

Conjugation

Unconjugated

Applications

WB; IHC; IF

Field of Research

Cell Biology; Epigenetics and Nuclear Signaling; Metabolism; Cancer

Purification

Protein A purified

Concentration

1 mg/mL

Dilution

WB 1:500-1:2000; IHC 1:200-1:1000; IF 1:50-1:100

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

25 kDa

Observed Molecular Weight

25 kDa

Isotype

IgG, κ