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Product details

Recombinant COPS3 Monoclonal Antibody

Catalog number AN301497L-01

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Price for AN301497L-01

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Size / count 50 µL

Specifications

Catalog number
AN301497L-01
Size / count
50 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
Abbreviation
COPS3
UniProt
Q9UNS2
Host
Rabbit
Reactivity
Human; Rat; Mouse
Immunogen
Recombinant human COPS3 fragment
Target
SGN; Csn; COPS; COPS3; CSN3; SGN3; Constitutive photomorphogenic homolog subunit 3; COP 9 (constitutive photomorphogenic) subunit 3; COP 9 complex homolog subunit 3; COP 9 complex S3; COP 9 complex subunit 3; COP 9 constitutive photomorphogenic homolog subunit 3; COP 9 homolog; COP 9 signalosome complex subunit 3; COP 9 signalosome subunit 3; COP 9 subunit 3; COP9 (constitutive photomorphogenic) subunit 3; COP9 complex homolog subunit 3; COP9 complex S3; COP9 complex subunit 3; COP9 constitutive photomorphogenic homolog subunit 3; COP9 homolog; COP9 signalosome complex subunit 3; COP9 signalosome subunit 3; COP9 subunit 3; COPS 3; CSN 3; JAB 1 containing signalosome subunit 3; JAB1 containing signalosome subunit 3; JAB1-containing signalosome subunit 3; SGN 3; Signalosome subunit 3
Clonality
Monoclonal, Recombinant
Clone
A192
Conjugation
Unconjugated
Applications
WB; IHC; IF
Field of Research
Neuroscience; Cell Biology
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:500-1:1000; IHC 1:50-1:100; IF 1:50
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
44 kDa
Observed Molecular Weight
44 kDa
Isotype
IgG, κ

Frequently Asked Questions

What is the catalog number for Recombinant COPS3 Monoclonal Antibody?

The catalog number for Recombinant COPS3 Monoclonal Antibody is AN301497L.

What sizes are available for Recombinant COPS3 Monoclonal Antibody?

Recombinant COPS3 Monoclonal Antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does Recombinant COPS3 Monoclonal Antibody come in?

Recombinant COPS3 Monoclonal Antibody is available in 2 different pack sizes.

Is Recombinant COPS3 Monoclonal Antibody in stock?

Recombinant COPS3 Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant COPS3 Monoclonal Antibody?

Recombinant COPS3 Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Recombinant COPS3 Monoclonal Antibody?

Estimated delivery time for Recombinant COPS3 Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant COPS3 Monoclonal Antibody?

The safety data sheet for Recombinant COPS3 Monoclonal Antibody is available here: https://789.bio/eb/axSgyThu.

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

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