Recombinant HLA-DPA1 Monoclonal Antibody

Specifications

Catalog number

AN301550L-01

Size / count

50 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides presented by MHC class II molecules are generated mostly by degradation of proteins that access the endocytic route, where they are processed by lysosomal proteases and other hydrolases. Exogenous antigens that have been endocytosed by the APC are thus readily available for presentation via MHC II molecules, and for this reason this antigen presentation pathway is usually referred to as exogenous.

Abbreviation

HLA-DPA1

UniProt

P20036

Host

Rabbit

Reactivity

Human; Mouse

Immunogen

Recombinant human HLA-DPA1 fragment

Target

PLT; HLA-DPA; HLA-DPA1; DP (W3) ; DP (W4) ; HLA-DP1A; HLADP; HLASB; PLT1; class II; HLA class II histocompatibility antigen DP alpha 1 chain; HLA class II histocompatibility antigen DP alpha chain; HLA DP1A; HLA DPA 1; HLA SB alpha chain; HLADPA1; HLASB histocompatibility type; Human MHC class II HLA SB alpha gene; Major histocompatibility complex class II DP alpha 1; MHC class II antigen; MHC class II DP3 alpha; MHC class II DPA1; MHC class II HLA DPA1 antigen; Primed lymphocyte test 1

Clonality

Monoclonal, Recombinant

Clone

A249

Conjugation

Unconjugated

Applications

WB; IHC; IF

Field of Research

Immunology

Purification

Protein A purified

Concentration

1 mg/mL

Dilution

WB 1:500-1:1000; IHC 1:200-1:1000; IF 1:50

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

29 kDa

Observed Molecular Weight

33 kDa

Isotype

IgG, κ