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Product details

Recombinant HMGB1 Monoclonal Antibody

Catalog number AN301554L-01

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Price for AN301554L-01

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Size / count 50 µL

Specifications

Catalog number
AN301554L-01
Size / count
50 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
Multifunctional redox sensitive protein with various roles in different cellular compartments. In the nucleus is one of the major chromatin-associated non-histone proteins and acts as a DNA chaperone involved in replication, transcription, chromatin remodeling, V (D) J recombination, DNA repair and genome stability. Proposed to be an universal biosensor for nucleic acids. Promotes host inflammatory response to sterile and infectious signals and is involved in the coordination and integration of innate and adaptive immune responses. In the cytoplasm functions as sensor and/or chaperone for immunogenic nucleic acids implicating the activation of TLR9-mediated immune responses, and mediates autophagy. Acts as danger associated molecular pattern (DAMP) molecule that amplifies immune responses during tissue injury.
Abbreviation
HMGB1
UniProt
P09429
Host
Rabbit
Reactivity
Human; Rat; Mouse
Immunogen
Recombinant human HMGB1 fragment
Target
SBP; HMGB; High Mobility Group Protein; High mobility group protein B; HMG; HMG-1; HMG1; HMG3; SBP-1; HMGB1; Amphoterin; High Mobility Group Protein 1; High mobility group protein B1; High mobility group protein 1 (HMG-1) ; High mobility group protein 1; high mobility group protein B1; high-mobility group box 1; HMG1; HMG-1; HMG1DKFZp686A04236; HMG3; HMGB1; SBP-1; Chromosomal protein; DKFZp686A04236; High mobility group 1; High mobility group box 1; high-mobility group (nonhistone chromosomal) protein 1; HMGB 1; nonhistone; NONHISTONE CHROMOSOMAL PROTEIN HMG1; SBP 1; Sulfoglucuronyl carbohydrate binding protein
Clonality
Monoclonal, Recombinant
Clone
A253
Conjugation
Unconjugated
Applications
WB; IHC; FCM; IP
Field of Research
Epigenetics and Nuclear Signaling
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:200-1:1000; FCM 1:50-1:100; IP 1:25
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
25 kDa
Observed Molecular Weight
25 kDa
Isotype
IgG, κ

Frequently Asked Questions

What is the catalog number for Recombinant HMGB1 Monoclonal Antibody?

The catalog number for Recombinant HMGB1 Monoclonal Antibody is AN301554L.

What sizes are available for Recombinant HMGB1 Monoclonal Antibody?

Recombinant HMGB1 Monoclonal Antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does Recombinant HMGB1 Monoclonal Antibody come in?

Recombinant HMGB1 Monoclonal Antibody is available in 2 different pack sizes.

Is Recombinant HMGB1 Monoclonal Antibody in stock?

Recombinant HMGB1 Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant HMGB1 Monoclonal Antibody?

Recombinant HMGB1 Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Recombinant HMGB1 Monoclonal Antibody?

Estimated delivery time for Recombinant HMGB1 Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant HMGB1 Monoclonal Antibody?

The safety data sheet for Recombinant HMGB1 Monoclonal Antibody is available here: https://789.bio/eb/lEepSCuf.

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

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