Recombinant HMGCR Monoclonal Antibody — image 1 of 2

Product details

Recombinant HMGCR Monoclonal Antibody

Catalog number AN301555L-01

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Price for AN301555L-01

Size / count 50 µL

Specifications

Catalog number: AN301555L-01
Size / count: 50 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: 3-Hydroxy-3-methylglutaryl-CoA reductase (HMGCR) is a transmembrane glycoprotein of the endoplasmic reticulum. It is the rate-limiting enzyme for cholesterol biosynthesis and non-sterol isoprenoid biosynthesis. Play a key role in cellular cholesterol homeostasis. The activity of HMGCR is regulated by negative feedback, in which cholesterol and other end products of the metabolic pathway inhibit the activity of HMGCR in a multivalent manner. Cholesterol inhibits reductase activity mainly by inhibiting the transcription rate of HMGCR gene. HMGCR is the main target of statins, which are a class of cholesterol-lowering drugs.
Abbreviation: HMGCR
UniProt: P04035
Host: Rabbit
Reactivity: Human; Mouse
Immunogen: Recombinant human HMG-CoA Reductase fragment
Target: LDLCQ; HMGCR; LDLCQ3;3-hydroxy-3-methylglutaryl-CoA reductase;3-hydroxy-3-methylglutaryl-CoA reductase; LDLCQ3;3-hydroxy-3-methylglutaryl-coenzyme A reductase; HMG-CoA reductase
Clonality: Monoclonal, Recombinant
Clone: A254
Conjugation: Unconjugated
Applications: WB; IF; FCM; IP
Field of Research: Cardiovascular; Signal Transduction; Cancer; Metabolism
Purification: Protein A purified
Concentration: 1 mg/mL
Dilution: WB 1:500-1:2000; IF 1:50; FCM 1:50-1:100; IP 1:25
Buffer: PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions: Ice bag
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 97 kDa
Observed Molecular Weight: 97 kDa
Isotype: IgG, κ

Frequently Asked Questions

What is the catalog number for Recombinant HMGCR Monoclonal Antibody?

The catalog number for Recombinant HMGCR Monoclonal Antibody is AN301555L.

What sizes are available for Recombinant HMGCR Monoclonal Antibody?

Recombinant HMGCR Monoclonal Antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does Recombinant HMGCR Monoclonal Antibody come in?

Recombinant HMGCR Monoclonal Antibody is available in 2 different pack sizes.

Is Recombinant HMGCR Monoclonal Antibody in stock?

Recombinant HMGCR Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant HMGCR Monoclonal Antibody?

Recombinant HMGCR Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Recombinant HMGCR Monoclonal Antibody?

Estimated delivery time for Recombinant HMGCR Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant HMGCR Monoclonal Antibody?

The safety data sheet for Recombinant HMGCR Monoclonal Antibody is available here: https://789.bio/eb/6rZ4TEhA.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.