Recombinant LPCAT1 Monoclonal Antibody

Specifications

Catalog number

AN301588L-01

Size / count

50 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

Exhibits acyltransferase activity. Exhibits acetyltransferase activity. Activity is calcium-independent. Catalyzes the conversion of lysophosphatidylcholine (1-acyl-sn-glycero-3-phosphocholine or LPC) into phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine or PC) . Catalyzes the conversion 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. Displays a clear preference for saturated fatty acyl-CoAs, and 1-myristoyl or 1-palmitoyl LPC as acyl donors and acceptors, respectively. Involved in platelet-activating factor (PAF) biosynthesis by catalyzing the conversion of the PAF precursor, 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF) into 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine (PAF) . May synthesize phosphatidylcholine in pulmonary surfactant, thereby playing a pivotal role in respiratory physiology. Involved in the regulation of lipid droplet number and siExhibits acyltransferase activity.

Abbreviation

LPCAT1

UniProt

Q8NF37

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant human LPCAT1 fragment

Target

AYTL; PFAAP; LPCAT1; AGPAT10; AGPAT9; AYTL2; LPCAT-1; PFAAP3; lpcat; lysoPAFAT

Clonality

Monoclonal, Recombinant

Clone

A287

Conjugation

Unconjugated

Applications

WB; IHC; IF

Purification

Protein A purified

Concentration

1 mg/mL

Dilution

WB 1:500-1:1000; IHC 1:50-1:100; IF 1:50

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

59 kDa

Observed Molecular Weight

59 kDa

Isotype

IgG, κ