Recombinant MCM5 Monoclonal Antibody

Specifications

Catalog number

AN301598L-01

Size / count

50 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Interacts with MCMBP.

Abbreviation

MCM5

UniProt

P33992

Host

Rabbit

Reactivity

Human; Rat; Mouse

Immunogen

Recombinant human MCM5 fragment

Target

MGC; Cell division cycle; DNA replication licensing factor MCM; Minichromosome maintenance complex component; P1-CDC; P1 CDC; CDC; MCM; MCM5; CDC46; P1-CDC46; CDC 46; CDC46 homolog; Cell division cycle 46; DNA replication licensing factor; DNA replication licensing factor MCM5; MCM 5; MGC5315; Minichromosome maintenance complex component 5; P1 CDC46; DNA replication licensing factor MCM 5; Minichromosome maintenance complex component 5; Minichromosome maintenance deficient (S. cerevisiae) 5; Minichromosome maintenance deficient 5; Minichromosome maintenance deficient protein 5

Clonality

Monoclonal, Recombinant

Clone

A301

Conjugation

Unconjugated

Applications

WB; IHC; IF

Field of Research

Epigenetics and Nuclear Signaling

Purification

Protein A purified

Concentration

1 mg/mL

Dilution

WB 1:500-1:1000; IHC 1:50-1:100; IF 1:50

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

82 kDa

Observed Molecular Weight

82 kDa

Isotype

IgG, κ