Recombinant NPM1 Monoclonal Antibody — image 1 of 5

Product details

Recombinant NPM1 Monoclonal Antibody

Catalog number AN301612L-01

Choose a variant (2 options)

Selecting a variant updates its price, size and availability.

Price for AN301612L-01

Size / count 50 µL

Specifications

Catalog number: AN301612L-01
Size / count: 50 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Involved in diverse cellular processes such as ribosome biogenesis, centrosome duplication, protein chaperoning, histone assembly, cell proliferation, and regulation of tumor suppressors p53/TP53 and ARF. Binds ribosome presumably to drive ribosome nuclear export. Associated with nucleolar ribonucleoprotein structures and bind single-stranded nucleic acids. Acts as a chaperonin for the core histones H3, H2B and H4. Stimulates APEX1 endonuclease activity on apurinic/apyrimidinic (AP) double-stranded DNA but inhibits APEX1 endonuclease activity on AP single-stranded RNA. May exert a control of APEX1 endonuclease activity within nucleoli devoted to repair AP on rDNA and the removal of oxidized rRNA molecules. In concert with BRCA2, regulates centrosome duplication. Regulates centriole duplication: phosphorylation by PLK2 is able to trigger centriole replication. Negatively regulates the activation of EIF2AK2/PKR and suppresses apoptosis through inhibition of EIF2AK2/PKR autophosphorylation. Antagonizes the inhibitory effect of ATF5 on cell proliferation and relieves ATF5-induced G2/M blockade. In complex with MYC enhances the transcription of MYC target genes.
Abbreviation: NPM1
UniProt: P06748
Host: Rabbit
Reactivity: Human; Rat; Mouse
Immunogen: Recombinant human NPM1 fragment
Target: B23; NPM; NPM1
Clonality: Monoclonal, Recombinant
Clone: A315
Conjugation: Unconjugated
Applications: WB; IHC; IF; FCM
Field of Research: Epigenetics and Nuclear Signaling
Purification: Protein A purified
Concentration: 1 mg/mL
Dilution: WB 1:500-1:2000; IHC 1:200-1:1000; IF 1:100-1:500; FCM 1:50-1:100
Buffer: PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions: Ice bag
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 33 kDa
Observed Molecular Weight: 37 kDa
Isotype: IgG, κ

Frequently Asked Questions

What is the catalog number for Recombinant NPM1 Monoclonal Antibody?

The catalog number for Recombinant NPM1 Monoclonal Antibody is AN301612L.

What sizes are available for Recombinant NPM1 Monoclonal Antibody?

Recombinant NPM1 Monoclonal Antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does Recombinant NPM1 Monoclonal Antibody come in?

Recombinant NPM1 Monoclonal Antibody is available in 2 different pack sizes.

Is Recombinant NPM1 Monoclonal Antibody in stock?

Recombinant NPM1 Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant NPM1 Monoclonal Antibody?

Recombinant NPM1 Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Recombinant NPM1 Monoclonal Antibody?

Estimated delivery time for Recombinant NPM1 Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant NPM1 Monoclonal Antibody?

The safety data sheet for Recombinant NPM1 Monoclonal Antibody is available here: https://789.bio/eb/JExHPbpU.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.