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Product details

Recombinant CDKN2A/p14ARF Monoclonal Antibody

Catalog number AN301615L-01

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Price for AN301615L-01

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Size / count 50 µL

Specifications

Catalog number
AN301615L-01
Size / count
50 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
Capable of inducing cell cycle arrest in G1 and G2 phases. Acts as a tumor suppressor. Binds to MDM2 and blocks its nucleocytoplasmic shuttling by sequestering it in the nucleolus. This inhibits the oncogenic action of MDM2 by blocking MDM2-induced degradation of p53 and enhancing p53-dependent transactivation and apoptosis. Also induces G2 arrest and apoptosis in a p53-independent manner by preventing the activation of cyclin B1/CDC2 complexes. Binds to BCL6 and down-regulates BCL6-induced transcriptional repression.
Abbreviation
CDKN2A/p14ARF
UniProt
Q8N726
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant human CDKN2A/p14ARF fragment
Target
CDKN; CDKN2; MLM; CDKN2A
Clonality
Monoclonal, Recombinant
Clone
A318
Conjugation
Unconjugated
Applications
WB; IHC; IF; IP
Field of Research
Cell Biology; Epigenetics and Nuclear Signaling; Cancer
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:200-1:1000; IF 1:50; IP 1:50-1:100
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
14 kDa
Observed Molecular Weight
14 kDa
Isotype
IgG, κ

Frequently Asked Questions

What is the catalog number for Recombinant CDKN2A/p14ARF Monoclonal Antibody?

The catalog number for Recombinant CDKN2A/p14ARF Monoclonal Antibody is AN301615L.

What sizes are available for Recombinant CDKN2A/p14ARF Monoclonal Antibody?

Recombinant CDKN2A/p14ARF Monoclonal Antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does Recombinant CDKN2A/p14ARF Monoclonal Antibody come in?

Recombinant CDKN2A/p14ARF Monoclonal Antibody is available in 2 different pack sizes.

Is Recombinant CDKN2A/p14ARF Monoclonal Antibody in stock?

Recombinant CDKN2A/p14ARF Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant CDKN2A/p14ARF Monoclonal Antibody?

Recombinant CDKN2A/p14ARF Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Recombinant CDKN2A/p14ARF Monoclonal Antibody?

Estimated delivery time for Recombinant CDKN2A/p14ARF Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant CDKN2A/p14ARF Monoclonal Antibody?

The safety data sheet for Recombinant CDKN2A/p14ARF Monoclonal Antibody is available here: https://789.bio/eb/th5WSRkn.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

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