Recombinant PAX8 Monoclonal Antibody

Specifications

Catalog number

AN301620L-01

Size / count

50 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

PAX8 is one of nine transcription factors within the PAX gene family. It has been observed to be expressed during embryonic development however expression attenuates after development in all but a few tissues. Research has indicated that over-expression of PAX proteins in general are not an initiating event in tumorgenesis however they may facilitate malignant development. PAX8 is expressed in 80-96% of all High-grade serous carcinomas (HGSC) and is commonly used as a marker for the disease. In addition PAX8 has become a useful biomarker for differentiating between mullerian mucinous and non-mullerian tumors. PAX8 has also been associated with neoplasms in the kidney and thyroid.

Abbreviation

PAX8

UniProt

Q06710

Host

Rabbit

Reactivity

Human; Rat; Mouse

Immunogen

Recombinant human PAX8 fragment

Target

Paired box; Paired box gene; Paired domain gene; paired box homeotic gene; PAX; PAX8; OTTHUMP00000158659; OTTHUMP00000158660; OTTHUMP00000203723; OTTHUMP00000203724; Paired box 8; Paired box gene 8; paired box homeotic gene 8; Paired box protein Pax 8; Paired box protein Pax-8; Paired domain gene 8; PAX 8

Clonality

Monoclonal, Recombinant

Clone

A323

Conjugation

Unconjugated

Applications

IHC; IF

Field of Research

Neuroscience; Epigenetics and Nuclear Signaling

Purification

Protein A purified

Concentration

1 mg/mL

Dilution

IHC 1:50-1:100; IF 1:50

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Isotype

IgG, κ