Recombinant STING Monoclonal Antibody — image 1 of 3

Product details

Recombinant STING Monoclonal Antibody

Catalog number AN301666L-01

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Price for AN301666L-01

Size / count 50 µL

Specifications

Catalog number: AN301666L-01
Size / count: 50 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: STING has several transmembrane domains, and is expressed in a variety of endothelial cells, epithelial cells and hematopoietic liver cells. STING participates in the DNA-mediated innate immune response. Non-CpG double-stranded DNA from viruses or bacteria binds to cGAS protein and is catalyzed to the second messenger cGAMP; then the dimerized STING binds to cGAMP and undergoes conformational changes. Through the autophagsome and the endoplasmic reticulum and the Golgi apparatus, it further enters the cytoplasm. During the period, it is ubiquitinated and recruited TBK1 protein, then phosphorylated, and then combined with IRF3; then IRF3 is phosphorylated and enters the nucleus to induce the expression of IFNs, etc. In conclusion, it can enhance the body's immune ability and kill bacteria, viruses and other pathogens to a greater extent.
Abbreviation: STING
UniProt: Q86WV6
Host: Rabbit
Reactivity: Human
Immunogen: Recombinant human STING fragment
Target: NET; TMEM; TMEM173; ERIS; MITA; MPYS; NET23; SAVI; STING; hMITA; hSTING; Mediator of IRF3 activation; Stimulator of interferon genes protein; STING1; endoplasmic reticulum IFN stimulator; Endoplasmic reticulum interferon stimulator; FLJ38577; Mitochondrial mediator of IRF3 activation; N terminal methionine proline tyrosine serine plasma membrane tetraspanner; Stimulator of interferon genes; TM173; Transmembrane protein 173
Clonality: Monoclonal, Recombinant
Clone: A369
Conjugation: Unconjugated
Applications: WB; IHC; IF
Field of Research: Immunology; Signal Transduction; Epigenetics and Nuclear Signaling; Cancer
Purification: Protein A purified
Concentration: 1 mg/mL
Dilution: WB 1:500-1:2000; IHC 1:200-1:1000; IF 1:50
Buffer: PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions: Ice bag
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 42 kDa
Observed Molecular Weight: 36 kDa
Isotype: IgG, κ

Frequently Asked Questions

What is the catalog number for Recombinant STING Monoclonal Antibody?

The catalog number for Recombinant STING Monoclonal Antibody is AN301666L.

What sizes are available for Recombinant STING Monoclonal Antibody?

Recombinant STING Monoclonal Antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does Recombinant STING Monoclonal Antibody come in?

Recombinant STING Monoclonal Antibody is available in 2 different pack sizes.

Is Recombinant STING Monoclonal Antibody in stock?

Recombinant STING Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant STING Monoclonal Antibody?

Recombinant STING Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Recombinant STING Monoclonal Antibody?

Estimated delivery time for Recombinant STING Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant STING Monoclonal Antibody?

The safety data sheet for Recombinant STING Monoclonal Antibody is available here: https://789.bio/eb/xz3YY63q.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.