Recombinant RMP/C19orf2 Monoclonal Antibody

Specifications

Catalog number

AN301683L-01

Size / count

50 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

Involved in gene transcription regulation. Acts as a transcriptional repressor in concert with the corepressor UXT to regulate androgen receptor (AR) transcription. May act as a tumor suppressor to repress AR-mediated gene transcription and to inhibit anchorage-independent growth in prostate cancer cells. Required for cell survival in ovarian cancer cells. Together with UXT, associates with chromatin to the NKX3-1 promoter region. Antagonizes transcriptional modulation via hepatitis B virus X protein.

Abbreviation

RMP/C19orf2

UniProt

O94763

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant human RMP/C19orf2 fragment

Target

NNX; PPP1R; C19orf; C19orf2; NNX3; PPP1R19; RMP; URI; URI1; prefoldin-like chaperone; Chromosome 19 open reading frame 2; NNX3; NNX3 protein; Protein NNX3; Protein phosphatase 1 regulatory subunit 19; RMP; RNA polymerase II subunit 5 mediating protein; RNA polymerase II subunit 5-mediating protein; RPB5 mediating protein; RPB5-mediating protein; Unconventional prefoldin RPB5 interactor; Unconventional prefoldin RPB5 interactor 1

Clonality

Monoclonal, Recombinant

Clone

A386

Conjugation

Unconjugated

Applications

WB; IHC; IF

Field of Research

Epigenetics and Nuclear Signaling

Purification

Protein A purified

Concentration

1 mg/mL

Dilution

WB 1:500-1:1000; IHC 1:200-1:1000; IF 1:50

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

60 kDa

Observed Molecular Weight

79 kDa

Isotype

IgG, κ