Recombinant Na+/K+ ATPase alpha-1 Monoclonal Antibody

Specifications

Catalog number

AN301712L-01

Size / count

50 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.

Abbreviation

Na+/K+ ATPase alpha-1

UniProt

P05023

Host

Rabbit

Reactivity

Human; Rat; Mouse

Immunogen

Recombinant human Na+/K+ ATPase alpha-1 fragment

Target

ATPase Na+/K+ transporting subunit alpha; HOMGSMR; ATP1A1; ATPase Na+/K+ transporting subunit alpha 1; ATP1A; CMT2DD; HOMGSMR2; A1A1; AT1A1; Atpa-1; ATPase Na+/K+ transporting alpha 1 polypeptide; BC010319; EC 3.6.3.9; K ATPase alpha 1 subunit; K+ ATPase alpha subunit; MGC3285; MGC38419; MGC51750; Na K ATPase alpha A catalytic polypeptide; Na K ATPase catalytic subunit alpha A protein; Na (+) /K (+) ATPase 1; Na (+) /K (+) ATPase alpha-1 subunit; Na+; Na+/K+ ATPase alpha 1 subunit; Na+/K+ ATPase 1; Nkaa1b; Sodium potassium ATPase alpha 1 polypeptide; Sodium pump 1; Sodium pump subunit alpha-1; Sodium/potassium-transporting ATPase subunit alpha-1; sodium-potassium ATPase catalytic subunit alpha-1

Clonality

Monoclonal, Recombinant

Clone

A420

Conjugation

Unconjugated

Applications

WB; IHC; IF

Field of Research

Tags & Cell Markers; Signal Transduction; Neuroscience; Cancer; Metabolism; Isotype; Loading Controls

Purification

Protein A purified

Concentration

1 mg/mL

Dilution

WB 1:500-1:2000; IHC 1:200-1:1000; IF 1:50

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

113 kDa

Observed Molecular Weight

113 kDa

Isotype

IgG, κ