Recombinant Topoisomerase I Monoclonal Antibody — image 1 of 2

Product details

Recombinant Topoisomerase I Monoclonal Antibody

Catalog number AN301767L-01

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Price for AN301767L-01

Size / count 50 µL

Specifications

Catalog number: AN301767L-01
Size / count: 50 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: DNA topoisomerases play essential roles in many DNA metabolic processes including DNA repair. Topoisomerases can introduce DNA damage upon exposure to drugs that stabilize the covalent protein-DNA intermediate of the topoisomerase reaction. Lesions in DNA are also able to trap topoisomerase-DNA intermediates. DNA topoisomerase I (Top1) catalyzes the relaxation of supercoiled DNA by a mechanism of transient DNA strand cleavage characterized by the formation of a phosphotyrosyl bond between the DNA end and active site tyrosine.
Abbreviation: Topoisomerase I
UniProt: P11387
Host: Rabbit
Reactivity: Human; Rat; Mouse
Immunogen: Recombinant human Topoisomerase I fragment
Target: TOP; TOP1; TOPI
Clonality: Monoclonal, Recombinant
Clone: A475
Conjugation: Unconjugated
Applications: WB; IHC; IF; FCM; IP
Field of Research: Epigenetics and Nuclear Signaling; Cancer
Purification: Protein A purified
Concentration: 1 mg/mL
Dilution: WB 1:500-1:2000; IHC 1:100-1:500; IF 1:50; FCM 1:50-1:100; IP 1:25-1:50
Buffer: PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions: Ice bag
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 91 kDa
Observed Molecular Weight: 108 kDa
Isotype: IgG, κ

Frequently Asked Questions

What is the catalog number for Recombinant Topoisomerase I Monoclonal Antibody?

The catalog number for Recombinant Topoisomerase I Monoclonal Antibody is AN301767L.

What sizes are available for Recombinant Topoisomerase I Monoclonal Antibody?

Recombinant Topoisomerase I Monoclonal Antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does Recombinant Topoisomerase I Monoclonal Antibody come in?

Recombinant Topoisomerase I Monoclonal Antibody is available in 2 different pack sizes.

Is Recombinant Topoisomerase I Monoclonal Antibody in stock?

Recombinant Topoisomerase I Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant Topoisomerase I Monoclonal Antibody?

Recombinant Topoisomerase I Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Recombinant Topoisomerase I Monoclonal Antibody?

Estimated delivery time for Recombinant Topoisomerase I Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant Topoisomerase I Monoclonal Antibody?

The safety data sheet for Recombinant Topoisomerase I Monoclonal Antibody is available here: https://789.bio/eb/sV5hyHjB.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.