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Product details

Recombinant PTP1B Monoclonal Antibody

Catalog number AN301798L-01

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Price for AN301798L-01

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Size / count 50 µL

Specifications

Catalog number
AN301798L-01
Size / count
50 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
PTP1B is the founding member of the protein tyrosine phosphatase (PTP) family and PTPs catalyze the hydrolysis of the phosphate monoesters specifically on tyrosine residues. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTP1B has been shown to act as a negative regulator of insulin signaling by dephosphorylating the phosphotryosine residues of insulin receptor kinase. PTP1B was also reported to dephosphorylate epidermal growth factor receptor kinase, as well as JAK2 and TYK2 kinases, which implicated the role of this PTP in cell growth control, and cell response to interferon stimulation.
Abbreviation
PTP1B
UniProt
P18031
Host
Rabbit
Reactivity
Human; Rat; Mouse
Immunogen
Recombinant human PTP1B fragment
Target
PTPN; PTPN1; PTP1B
Clonality
Monoclonal, Recombinant
Clone
A510
Conjugation
Unconjugated
Applications
WB; IHC; IF
Field of Research
Signal Transduction; Cardiovascular
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:200-1:1000; IF 1:50
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
50 kDa
Observed Molecular Weight
50 kDa
Isotype
IgG, κ

Frequently Asked Questions

What is the catalog number for Recombinant PTP1B Monoclonal Antibody?

The catalog number for Recombinant PTP1B Monoclonal Antibody is AN301798L.

What sizes are available for Recombinant PTP1B Monoclonal Antibody?

Recombinant PTP1B Monoclonal Antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does Recombinant PTP1B Monoclonal Antibody come in?

Recombinant PTP1B Monoclonal Antibody is available in 2 different pack sizes.

Is Recombinant PTP1B Monoclonal Antibody in stock?

Recombinant PTP1B Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant PTP1B Monoclonal Antibody?

Recombinant PTP1B Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Recombinant PTP1B Monoclonal Antibody?

Estimated delivery time for Recombinant PTP1B Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant PTP1B Monoclonal Antibody?

The safety data sheet for Recombinant PTP1B Monoclonal Antibody is available here: https://789.bio/eb/l2dxBo8w.

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

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