Recombinant Thymidylate Synthase Monoclonal Antibody

Catalog number AN301812L-01

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Price for AN301812L-01

Size / count 50 µL

Specifications

Catalog number: AN301812L-01
Size / count: 50 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Thymidylate synthase is a homodimer composed of two 30 kDa subunits, which catalyze the methylation of deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP), an essential step in the formation of thymine nucleotides. Thymidylate synthase is an intracellular enzyme that provides the sole de novo source of thymidylate, making it a required enzyme in DNA biosynthesis with activity highest in proliferating cells. Being the exclusive source of dTMP, investigators have concluded that TS is also an important target for anticancer agents such as 5-fluorouracil (5-FU) . 5-FU acts as a TS inhibitor and is active against solid tumors such as colon, breast, head, and neck.
Abbreviation: Thymidylate Synthase
UniProt: P04818
Host: Rabbit
Reactivity: Human; Rat; Mouse
Immunogen: Recombinant human Thymidylate Synthase fragment
Target: HST; OK/SW-cl; TYMS; HST422; TMS; TS; thymidylate synthase; OK/SW-cl.29; HST422; thymidylate synthase; TMS; thymidylate synthetase
Clonality: Monoclonal, Recombinant
Clone: A524
Conjugation: Unconjugated
Applications: WB; IF; FCM
Field of Research: Epigenetics and Nuclear Signaling; Metabolism
Purification: Protein A purified
Concentration: 1 mg/mL
Dilution: WB 1:500-1:2000; IF 1:50; FCM 1:50-1:100
Buffer: PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions: Ice bag
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 36 kDa
Observed Molecular Weight: 36 kDa
Isotype: IgG, κ

Frequently Asked Questions

What is the catalog number for Recombinant Thymidylate Synthase Monoclonal Antibody?

The catalog number for Recombinant Thymidylate Synthase Monoclonal Antibody is AN301812L.

What sizes are available for Recombinant Thymidylate Synthase Monoclonal Antibody?

Recombinant Thymidylate Synthase Monoclonal Antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does Recombinant Thymidylate Synthase Monoclonal Antibody come in?

Recombinant Thymidylate Synthase Monoclonal Antibody is available in 2 different pack sizes.

Is Recombinant Thymidylate Synthase Monoclonal Antibody in stock?

Recombinant Thymidylate Synthase Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant Thymidylate Synthase Monoclonal Antibody?

Recombinant Thymidylate Synthase Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Recombinant Thymidylate Synthase Monoclonal Antibody?

Estimated delivery time for Recombinant Thymidylate Synthase Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant Thymidylate Synthase Monoclonal Antibody?

The safety data sheet for Recombinant Thymidylate Synthase Monoclonal Antibody is available here: https://789.bio/eb/b8mtwWbW.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.