Recombinant CD3D Monoclonal Antibody — image 1 of 2

Product details

Recombinant CD3D Monoclonal Antibody

Catalog number AN301813L-01

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Price for AN301813L-01

Size / count 50 µL

Specifications

Catalog number: AN301813L-01
Size / count: 50 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: CD3D is a component of the TCR-CD3 complex, which is present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of downstream signaling pathways. In addition, CD3D plays an essential role in thymocyte differentiation. It participates in correct intracellular TCR-CD3 complex assembly and surface expression. In absence of a functional TCR-CD3 complex, thymocytes are unable to differentiate properly. It interacts with CD4 and CD8 and thus serves to establish a functional link between the TCR and coreceptors CD4 and CD8, which is needed for activation and positive selection of CD4 or CD8 T-cells.
Abbreviation: CD3D
UniProt: P04234
Host: Rabbit
Reactivity: Human
Immunogen: Recombinant human CD3D fragment
Target: IMD; CD3D; CD3-DELTA; IMD19; T3D; T-Cell Receptor T3 Delta Chain; T-cell surface glycoprotein CD3 delta chain; T3; CD3 delta
Clonality: Monoclonal, Recombinant
Clone: A525
Conjugation: Unconjugated
Applications: WB; IHC; IF; FCM; IP
Field of Research: Immunology; Stem Cells
Purification: Protein A purified
Concentration: 1 mg/mL
Dilution: WB 1:2000-1:10000; IHC 1:200-1:1000; IF 1:50-1:200; FCM 1:50-1:100; IP 1:25-1:50
Buffer: PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions: Ice bag
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 19 kDa
Observed Molecular Weight: 23 kDa
Isotype: IgG, κ

Frequently Asked Questions

What is the catalog number for Recombinant CD3D Monoclonal Antibody?

The catalog number for Recombinant CD3D Monoclonal Antibody is AN301813L.

What sizes are available for Recombinant CD3D Monoclonal Antibody?

Recombinant CD3D Monoclonal Antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does Recombinant CD3D Monoclonal Antibody come in?

Recombinant CD3D Monoclonal Antibody is available in 2 different pack sizes.

Is Recombinant CD3D Monoclonal Antibody in stock?

Recombinant CD3D Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant CD3D Monoclonal Antibody?

Recombinant CD3D Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Recombinant CD3D Monoclonal Antibody?

Estimated delivery time for Recombinant CD3D Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant CD3D Monoclonal Antibody?

The safety data sheet for Recombinant CD3D Monoclonal Antibody is available here: https://789.bio/eb/bNZakHgo.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.