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Product details

Recombinant NF-kB2 p100/p52 Monoclonal Antibody

Catalog number AN301826L-01

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Price for AN301826L-01

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Size / count 50 µL

Specifications

Catalog number
AN301826L-01
Size / count
50 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. In a non-canonical activation pathway, the MAP3K14-activated CHUK/IKKA homodimer phosphorylates NFKB2/p100 associated with RelB, inducing its proteolytic processing to NFKB2/p52 and the formation of NF-kappa-B RelB-p52 complexes. NFKB2 appears to have dual functions such as cytoplasmic retention of attached NF-kappa-B proteins by p100 and generation of p52 by a cotranslational processing. The proteasome-mediated process ensures the production of both p52 and p100 and preserves their independent function.
Abbreviation
NF-kB2 p100/p52
UniProt
Q00653
Host
Rabbit
Reactivity
Human; Rat; Mouse
Immunogen
Recombinant human NF-kB2 p100/p52 fragment
Target
CVID; H2TF; NFKB; NF-kB; p49/p; LYT; CVID10; H2TF1; LYT-10; LYT10; NF-kB2; p100; p49/p100; p52; NFKB2; p105
Clonality
Monoclonal, Recombinant
Clone
A538
Conjugation
Unconjugated
Applications
WB; IHC; IF
Field of Research
Signal Transduction; Epigenetics and Nuclear Signaling
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:1000-1:5000; IHC 1:50-1:100; IF 1:50
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
97 kDa
Observed Molecular Weight
120 kDa
Isotype
IgG, κ

Frequently Asked Questions

What is the catalog number for Recombinant NF-kB2 p100/p52 Monoclonal Antibody?

The catalog number for Recombinant NF-kB2 p100/p52 Monoclonal Antibody is AN301826L.

What sizes are available for Recombinant NF-kB2 p100/p52 Monoclonal Antibody?

Recombinant NF-kB2 p100/p52 Monoclonal Antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does Recombinant NF-kB2 p100/p52 Monoclonal Antibody come in?

Recombinant NF-kB2 p100/p52 Monoclonal Antibody is available in 2 different pack sizes.

Is Recombinant NF-kB2 p100/p52 Monoclonal Antibody in stock?

Recombinant NF-kB2 p100/p52 Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant NF-kB2 p100/p52 Monoclonal Antibody?

Recombinant NF-kB2 p100/p52 Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Recombinant NF-kB2 p100/p52 Monoclonal Antibody?

Estimated delivery time for Recombinant NF-kB2 p100/p52 Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant NF-kB2 p100/p52 Monoclonal Antibody?

The safety data sheet for Recombinant NF-kB2 p100/p52 Monoclonal Antibody is available here: https://789.bio/eb/UTPkihxa.

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

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