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Product details

Recombinant HSD17B1 Monoclonal Antibody

Catalog number AN301846L-01

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Price for AN301846L-01

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Size / count 50 µL

Specifications

Catalog number
AN301846L-01
Size / count
50 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
HSD17B1 is a member of the 17beta-hydroxysteroid dehydrogenase family of short-chain dehydrogenases/reductases. It has a dual function in estrogen activation and androgen inactivation and plays a major role in establishing the estrogen E2 concentration gradient between serum and peripheral tissues. HSD17B1 catalyzes the last step in estrogen activation, using NADPH to convert estrogens E1 and E2 and androgens like 4-androstenedione, to testosterone. It has an N-terminal short-chain dehydrogenase domain with a cofactor binding site, and a narrow, hydrophobic C-terminal domain with a steroid substrate binding site. HSD17B1 is expressed primarily in the placenta and ovarian granulosa cells, and to a lesser extent, in the endometrium, adipose tissue, and prostate.
Abbreviation
HSD17B1
UniProt
P14061
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant human HSD17B1 fragment
Target
HSD; EDHB; HSD17B; SDR28C; HSD17B1;17-beta-HSD;20-alpha-HSD; E2DH; EDH17B2; EDHB17; HSD17; SDR28C1; E17KSR; EDH17B1;17 beta HSD 1;17 beta hydroxysteroid dehydrogenase type 1;17-beta-HSD 1;17-beta-hydroxysteroid dehydrogenase type 1;20 alpha-hydroxysteroid dehydrogenase; DHB1; Estradiol 17 beta dehydrogenase 1; Estradiol 17-beta-dehydrogenase 1; Hydroxysteroid (17 beta) dehydrogenase 1; member 1; MGC13814; Placental 17 beta hydroxysteroid dehydrogenase; Placental 17-beta-hydroxysteroid dehydrogenase; Short chain dehydrogenase/reductase family 28CE
Clonality
Monoclonal, Recombinant
Clone
A558
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Signal Transduction; Neuroscience; Cancer; Metabolism
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:5000-1:20000; IHC 1:1000-1:5000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
35 kDa
Observed Molecular Weight
35 kDa
Isotype
IgG, κ

Frequently Asked Questions

What is the catalog number for Recombinant HSD17B1 Monoclonal Antibody?

The catalog number for Recombinant HSD17B1 Monoclonal Antibody is AN301846L.

What sizes are available for Recombinant HSD17B1 Monoclonal Antibody?

Recombinant HSD17B1 Monoclonal Antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does Recombinant HSD17B1 Monoclonal Antibody come in?

Recombinant HSD17B1 Monoclonal Antibody is available in 2 different pack sizes.

Is Recombinant HSD17B1 Monoclonal Antibody in stock?

Recombinant HSD17B1 Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant HSD17B1 Monoclonal Antibody?

Recombinant HSD17B1 Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Recombinant HSD17B1 Monoclonal Antibody?

Estimated delivery time for Recombinant HSD17B1 Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant HSD17B1 Monoclonal Antibody?

The safety data sheet for Recombinant HSD17B1 Monoclonal Antibody is available here: https://789.bio/eb/dyL74bE0.

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

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