Recombinant IRAK1 Monoclonal Antibody

Catalog number AN301855L-01

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Price for AN301855L-01

Size / count 50 µL

Specifications

Catalog number: AN301855L-01
Size / count: 50 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: IRAK1 is the first member of the death domain containing protein kinase family that play a key role in initiating innate immune response against foreign pathogens. They are involved in Toll-like receptor (TLR) and interleukin-1 receptor (IL-1R) signaling pathways. Upon ligand binding to TLR/IL-1R, IRAK1 is recruited by MYD88 to the receptor-signaling complex, the association leads to IRAK1 phosphorylation by IRAK4 and subsequent autophosphorylation and kinase activation. Hyper-phosphorylated IRAK1 then disengages from the receptor complex, and forms a cytosolic IRAK1-TRAF6 complex. TRAF6 then interacts with TAK and TAB, resulting in eventual activation of the NF-κB and MAPK pathways. Phosphorylated IRAK1 also undergoes ubiquitin-mediated degradation or sumoylation, which results in nuclear translocation and transcriptional activation of inflammatory target genes.
Abbreviation: IRAK1
UniProt: P51617
Host: Rabbit
Reactivity: Human; Rat; Mouse
Immunogen: Recombinant human IRAK1 fragment
Target: IRAK1; IRAK; pelle
Clonality: Monoclonal, Recombinant
Clone: A567
Conjugation: Unconjugated
Applications: WB; IHC
Field of Research: Immunology; Signal Transduction; Cardiovascular
Purification: Protein A purified
Concentration: 1 mg/mL
Dilution: WB 1:200-1:1000; IHC 1:100-1:1000
Buffer: PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions: Ice bag
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 77 kDa
Observed Molecular Weight: 80 kDa
Isotype: IgG, κ

Frequently Asked Questions

What is the catalog number for Recombinant IRAK1 Monoclonal Antibody?

The catalog number for Recombinant IRAK1 Monoclonal Antibody is AN301855L.

What sizes are available for Recombinant IRAK1 Monoclonal Antibody?

Recombinant IRAK1 Monoclonal Antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does Recombinant IRAK1 Monoclonal Antibody come in?

Recombinant IRAK1 Monoclonal Antibody is available in 2 different pack sizes.

Is Recombinant IRAK1 Monoclonal Antibody in stock?

Recombinant IRAK1 Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant IRAK1 Monoclonal Antibody?

Recombinant IRAK1 Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Recombinant IRAK1 Monoclonal Antibody?

Estimated delivery time for Recombinant IRAK1 Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant IRAK1 Monoclonal Antibody?

The safety data sheet for Recombinant IRAK1 Monoclonal Antibody is available here: https://789.bio/eb/OoWhfytx.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.