Recombinant DR5 Monoclonal Antibody

Catalog number AN301856L-01

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Price for AN301856L-01

Size / count 50 µL

Specifications

Catalog number: AN301856L-01
Size / count: 50 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: DR5, also known as CD262, TNFRSF10B, TRAILR2, TRICK2 and KILLER, is a widely expressed single-pass type I membrane protein belonging to the tumour necrosis factor receptor superfamily (TNFRSF) . It is a receptor for TNF-related apoptosis-inducing ligand (TRAIL), which is a member of the tumor necrosis factor (TNF) family of cytokines and induces apoptosis in a wide variety of cells. DR5 contains two extracellular cysteine-rich repeats, typical for TNF receptor (TNFR) family members, and a cytoplasmic death domain (DD), through which DR5 is capable to transmit the apoptotic signal. In PDAC cells, especially Panc89 cells, it expresses additionally to the approximately 48 and 40 kDa forms of DR5, a faster migrating variant of DR5 of about 32 kDa. The TRAIL receptor 2 (death receptor 5, or DR5) forms receptor dimers in a ligand-dependent manner.
Abbreviation: DR5
UniProt: O14763
Host: Rabbit
Reactivity: Human
Immunogen: Recombinant human DR5 fragment
Target: UNQ; PRO; Death Receptor; TRAIL Receptor; TNF-Related Apoptosis-Inducing Ligand Receptor; TRICK; ZTNFR; TRAILR; TRAIL-R; KILLER/DR; CD262; DR5; KILLER; KILLER/DR5; TRAIL-R2; TRAILR2; TRICK2; TRICK2A; TRICK2B; TRICKB; ZTNFR9; TNFRSF10B; Death Receptor 5; TNF-Related Apoptosis-Inducing Ligand Receptor 2; TRAIL Receptor 2; Tumor Necrosis Factor Receptor Superfamily Member 10B; UNQ160; PRO186; DR5; KILLER; TNFRSF10b
Clonality: Monoclonal, Recombinant
Clone: A568
Conjugation: Unconjugated
Applications: WB; IHC
Field of Research: Cell Biology; Signal Transduction; Cancer; Cardiovascular
Purification: Protein A purified
Concentration: 1 mg/mL
Dilution: WB 1:1000-1:5000; IHC 1:200-1:1000
Buffer: PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions: Ice bag
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 48 kDa
Observed Molecular Weight: 40,48 kDa
Isotype: IgG, κ

Frequently Asked Questions

What is the catalog number for Recombinant DR5 Monoclonal Antibody?

The catalog number for Recombinant DR5 Monoclonal Antibody is AN301856L.

What sizes are available for Recombinant DR5 Monoclonal Antibody?

Recombinant DR5 Monoclonal Antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does Recombinant DR5 Monoclonal Antibody come in?

Recombinant DR5 Monoclonal Antibody is available in 2 different pack sizes.

Is Recombinant DR5 Monoclonal Antibody in stock?

Recombinant DR5 Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant DR5 Monoclonal Antibody?

Recombinant DR5 Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Recombinant DR5 Monoclonal Antibody?

Estimated delivery time for Recombinant DR5 Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant DR5 Monoclonal Antibody?

The safety data sheet for Recombinant DR5 Monoclonal Antibody is available here: https://789.bio/eb/xZBL09bV.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.