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Product details

Recombinant Glypican-3 Monoclonal Antibody

Catalog number AN301865L-01

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Price for AN301865L-01

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Size / count 50 µL

Specifications

Catalog number
AN301865L-01
Size / count
50 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
Glypican 3 belongs to Glypicans (GPCs), a family of glycosylphosphatidylinositol (GPI) -anchored heparan sulphate proteoglycans (HSPGs) that may play a role in the control of cell division and growth regulation. In mammals, there are six GPCs (GPC1 to GPC6), all of which have a similar core-protein size of approx. 60 kDa and the clustering of glycosaminoglycan attachment site near the C-terminus. They are tethered to the cell surface by GPI linkages, which can be cleaved by endogenous phospholipases, thus releasing the protein. Glypican 3 (GPC3) is highly expressed in many tissues during development and plays an important role in the regulation of embryonic growth. Loss-of-function mutations of GPC3 result in the Simpson-Golabi-Behmel overgrowth syndrome (SGBS), and Gpc-3 null mice display developmental overgrowth. In hepatocellular carcinoma (HCC), the overexpression of glypican 3 has been demonstrated to be a reliable diagnostic indicator.
Abbreviation
Glypican-3
UniProt
P51654
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant human Glypican-3 fragment
Target
MXR; GPC; UNQ; PRO; CDw; ADAM; Protein FOAP; Secreted glypican; Glypican proteoglycan; Sialic acid-binding Ig-like lectin; C20orf; OCI; GPC3; DGSX; GTR2-2; MXR7; OCI-5; SDYS; SGB; SGBS; SGBS1; glypican-3; CDw329; Glypican 3; Glypican proteoglycan 3; Glypican-3 [Precursor]; GTR2 2; Heparan sulphate proteoglycan; Intestinal protein OCI 5; Intestinal protein OCI-5; OCI 5; Protein FOAP-9; Secreted glypican-3; Sialic acid-binding Ig-like lectin 9; SIGLEC9; Siglec-9; ADAM33; C20orf153; UNQ873; PRO1891; OCI5
Clonality
Monoclonal, Recombinant
Clone
A577
Conjugation
Unconjugated
Applications
WB; IHC; IF
Field of Research
Stem Cells; Signal Transduction; Cancer; Developmental Biology
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:2000-1:10000; IHC 1:100-1:500; IF 1:50
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
70, 40 kDa
Observed Molecular Weight
15, 70 kDa
Isotype
IgG, κ

Frequently Asked Questions

What is the catalog number for Recombinant Glypican-3 Monoclonal Antibody?

The catalog number for Recombinant Glypican-3 Monoclonal Antibody is AN301865L.

What sizes are available for Recombinant Glypican-3 Monoclonal Antibody?

Recombinant Glypican-3 Monoclonal Antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does Recombinant Glypican-3 Monoclonal Antibody come in?

Recombinant Glypican-3 Monoclonal Antibody is available in 2 different pack sizes.

Is Recombinant Glypican-3 Monoclonal Antibody in stock?

Recombinant Glypican-3 Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant Glypican-3 Monoclonal Antibody?

Recombinant Glypican-3 Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Recombinant Glypican-3 Monoclonal Antibody?

Estimated delivery time for Recombinant Glypican-3 Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant Glypican-3 Monoclonal Antibody?

The safety data sheet for Recombinant Glypican-3 Monoclonal Antibody is available here: https://789.bio/eb/OFNsC1EM.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

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