Recombinant PRAS40 Monoclonal Antibody — image 1 of 2

Product details

Recombinant PRAS40 Monoclonal Antibody

Catalog number AN301877L-01

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Price for AN301877L-01

Size / count 50 µL

Specifications

Catalog number: AN301877L-01
Size / count: 50 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: PRAS40 is a proline-rich protein with a molecular weight of 40 kDa that acts as a substrate for the serine / threonine kinase Akt. PRAS40 also binds mTOR to transduce Akt signals to the mTOR complex. Inhibition of mTOR signaling stimulates PRAS40 binding to mTOR, which in turn inhibits mTOR activity. PRAS40 interacts with raptor in mTOR complex 1 (mTORC1) in insulin-deprived cells and inhibits the activation of the mTORC1 pathway mediated by the cell cycle protein Rheb. Phosphorylation of PRAS40 by Akt at Thr246 relieves PRAS40 inhibition of mTORC1. mTORC1 in turn phosphorylates PRAS40 at Ser183.
Abbreviation: PRAS40
UniProt: Q96B36
Host: Rabbit
Reactivity: Human; Rat; Mouse
Immunogen: Recombinant human PRAS40 fragment
Target: PRAS; AKT1 substrate; AKT1S; AKT1S1; Lobe; PRAS40; AKT1 substrate 1
Clonality: Monoclonal, Recombinant
Clone: A589
Conjugation: Unconjugated
Applications: WB; IHC
Field of Research: Cell Biology; Neuroscience; Signal Transduction
Purification: Protein A purified
Concentration: 1 mg/mL
Dilution: WB 1:500-1:1000; IHC 1:50-1:200
Buffer: PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions: Ice bag
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 27 kDa
Observed Molecular Weight: 40 kDa
Isotype: IgG, κ

Frequently Asked Questions

What is the catalog number for Recombinant PRAS40 Monoclonal Antibody?

The catalog number for Recombinant PRAS40 Monoclonal Antibody is AN301877L.

What sizes are available for Recombinant PRAS40 Monoclonal Antibody?

Recombinant PRAS40 Monoclonal Antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does Recombinant PRAS40 Monoclonal Antibody come in?

Recombinant PRAS40 Monoclonal Antibody is available in 2 different pack sizes.

Is Recombinant PRAS40 Monoclonal Antibody in stock?

Recombinant PRAS40 Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant PRAS40 Monoclonal Antibody?

Recombinant PRAS40 Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Recombinant PRAS40 Monoclonal Antibody?

Estimated delivery time for Recombinant PRAS40 Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant PRAS40 Monoclonal Antibody?

The safety data sheet for Recombinant PRAS40 Monoclonal Antibody is available here: https://789.bio/eb/fkg7rc6T.

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.