Recombinant Non-Phospho (Active) β-Catenin (Ser33, Ser37, Thr41) Monoclonal Antibody — image 1 of 3

Product details

Recombinant Non-Phospho (Active) β-Catenin (Ser33, Ser37, Thr41) Monoclonal Antibody

Catalog number AN301881L-01

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Price for AN301881L-01

Size / count 50 µL

Specifications

Catalog number: AN301881L-01
Size / count: 50 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Β-catenin is a key downstream effector in the Wnt signaling pathway. It is implicated in two major biological processes in vertebrates: early embryonic development and tumorigenesis. CK1 phosphorylates β-catenin at Ser45. This phosphorylation event primes β-catenin for subsequent phosphorylation by GSK-3β. GSK-3β destabilizes β-catenin by phosphorylating it at Ser33, Ser37, and Thr41. Mutations at these sites result in the stabilization of β-catenin protein levels and have been found in many tumor cell lines.Non-phospho (Active) β-Catenin (Ser33/37/Thr41) Rabbit mAb specifically recognizes β-catenin that is non-phosphorylated at Ser33, Ser33 or Thr41. Non-phospho β-Catenin (Ser33, Ser33 or Thr41) protein is useful as a readout of stabilized β-catenin protein, and therefore functionally active in cell-cell adhesion and mediating transcriptional activity via the canonical Wnt signaling pathway.
Abbreviation: Non-Phospho (Active) β-Catenin (Ser33, Ser37, Thr41)
UniProt: P35222
Host: Rabbit
Reactivity: Human; Rat; Mouse
Immunogen: Recombinant human Non-phospho (Active) β-Catenin (Ser33/37/Thr41) fragment
Target: MRD; PRO; Catenin beta; SW-cl; OK/SW-cl; CTNNB; MRD19; armadillo; beta Catenin; CTNNB1; Beta-catenin; Catenin beta-1; OK; SW-cl.35; OK/SW-cl.35; PRO2286;88kDa; beta 1; Cadherin associated protein; Catenin (cadherin associated protein) ; Catenin beta 1; CATNB; CHBCAT; CTNB1; DKFZp686D02253; FLJ25606; FLJ37923; OTTHUMP00000162082; OTTHUMP00000165222; OTTHUMP00000165223; OTTHUMP00000209288; OTTHUMP00000209289
Clonality: Monoclonal, Recombinant
Clone: A593
Conjugation: Unconjugated
Applications: WB; IHC; IF
Field of Research: Signal Transduction; Neuroscience; Stem Cells; Cancer; Cardiovascular
Purification: Protein A purified
Concentration: 1 mg/mL
Dilution: WB 1:500-1:1000; IHC 1:100-1:500; IF 1:50
Buffer: PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions: Ice bag
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 85 kDa
Observed Molecular Weight: 100 kDa
Isotype: IgG, κ

Frequently Asked Questions

What is the catalog number for Recombinant Non-Phospho (Active) β-Catenin (Ser33, Ser37, Thr41) Monoclonal Antibody?

The catalog number for Recombinant Non-Phospho (Active) β-Catenin (Ser33, Ser37, Thr41) Monoclonal Antibody is AN301881L.

What sizes are available for Recombinant Non-Phospho (Active) β-Catenin (Ser33, Ser37, Thr41) Monoclonal Antibody?

Recombinant Non-Phospho (Active) β-Catenin (Ser33, Ser37, Thr41) Monoclonal Antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does Recombinant Non-Phospho (Active) β-Catenin (Ser33, Ser37, Thr41) Monoclonal Antibody come in?

Recombinant Non-Phospho (Active) β-Catenin (Ser33, Ser37, Thr41) Monoclonal Antibody is available in 2 different pack sizes.

Is Recombinant Non-Phospho (Active) β-Catenin (Ser33, Ser37, Thr41) Monoclonal Antibody in stock?

Recombinant Non-Phospho (Active) β-Catenin (Ser33, Ser37, Thr41) Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant Non-Phospho (Active) β-Catenin (Ser33, Ser37, Thr41) Monoclonal Antibody?

Recombinant Non-Phospho (Active) β-Catenin (Ser33, Ser37, Thr41) Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Recombinant Non-Phospho (Active) β-Catenin (Ser33, Ser37, Thr41) Monoclonal Antibody?

Estimated delivery time for Recombinant Non-Phospho (Active) β-Catenin (Ser33, Ser37, Thr41) Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant Non-Phospho (Active) β-Catenin (Ser33, Ser37, Thr41) Monoclonal Antibody?

The safety data sheet for Recombinant Non-Phospho (Active) β-Catenin (Ser33, Ser37, Thr41) Monoclonal Antibody is available here: https://789.bio/eb/JX6y3Ce5.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.