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Product details

Recombinant SLC7A5/LAT1 Monoclonal Antibody

Catalog number AN301897L-01

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Price for AN301897L-01

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Size / count 50 µL

Specifications

Catalog number
AN301897L-01
Size / count
50 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
L-type amino acid transporter 1 (LAT1), also known as Solute carrier family 7 member 5 (SLC7A5), is a high-affinity neutral transporter of larger amino acids. It facilitates the cellular amino acid uptake in a sodium independent manner and selectively transports D-and L-isomers of small neutral amino acids. LAT1 also regulates amino acid exchange in conjunction with solute carrier family 1 member 5 (SLC1A5) . Transport of thyroid hormones across the placenta is established via LAT1 during normal fetal development. LAT1 promotes neuronal cell proliferation by regulating the transport of amino acids across the blood brain barrier. LAT1 is upregulated in various cancer types including breast cancer, lung cancer, prostate cancer, and gliomas. High expression of LAT1 is detected in non-small cell lung cancer with lymph node metastases. Increased LAT1 expression is a novel biomarker of high-grade malignancy in prostate cancers. Inhibition of LAT1 suppresses tumor cell growth in several tumor types.
Abbreviation
SLC7A5/LAT1
UniProt
Q01650
Host
Rabbit
Reactivity
Human; Rat; Mouse
Immunogen
Recombinant human SLC7A5/LAT1 fragment
Target
LAT; MPE; hLAT; SLC7A; SLC7A5;4F2LC; CD98; D16S469E; E16; LAT1; MPE16; hLAT1; CD98LC
Clonality
Monoclonal, Recombinant
Clone
A613
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Signal Transduction; Metabolism
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:2000-1:10000; IHC 1:200-1:1000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
55 kDa
Observed Molecular Weight
39 kDa
Isotype
IgG, κ

Frequently Asked Questions

What is the catalog number for Recombinant SLC7A5/LAT1 Monoclonal Antibody?

The catalog number for Recombinant SLC7A5/LAT1 Monoclonal Antibody is AN301897L.

What sizes are available for Recombinant SLC7A5/LAT1 Monoclonal Antibody?

Recombinant SLC7A5/LAT1 Monoclonal Antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does Recombinant SLC7A5/LAT1 Monoclonal Antibody come in?

Recombinant SLC7A5/LAT1 Monoclonal Antibody is available in 2 different pack sizes.

Is Recombinant SLC7A5/LAT1 Monoclonal Antibody in stock?

Recombinant SLC7A5/LAT1 Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant SLC7A5/LAT1 Monoclonal Antibody?

Recombinant SLC7A5/LAT1 Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Recombinant SLC7A5/LAT1 Monoclonal Antibody?

Estimated delivery time for Recombinant SLC7A5/LAT1 Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant SLC7A5/LAT1 Monoclonal Antibody?

The safety data sheet for Recombinant SLC7A5/LAT1 Monoclonal Antibody is available here: https://789.bio/eb/y2UrWyI2.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

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