Recombinant SMARCA2/BRM Monoclonal Antibody

Specifications

Catalog number

AN301908L-01

Size / count

50 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

SMARCA2, also named as BRM, is a transcriptional coactivator cooperating with nuclear hormone receptors to potentiate transcriptional activation. SMARCA2 is involved in vitamin D-coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), which is required for the ligand-bound VDR-mediated transrepression of the CYP27B1 gene.

Abbreviation

SMARCA2/BRM

UniProt

P51531

Host

Rabbit

Reactivity

Human; Rat; Mouse

Immunogen

Recombinant human SMARCA2/BRM fragment

Target

SNF2L; SMARCA; BAF190B; BRM; SNF2A; SNF2L2; SMARCA2; ATP dependent helicase SMARCA2; ATP-dependent helicase SMARCA2; BAF190; BRG1-associated factor 190B; FLJ36757; Global transcription activator homologous sequence; hBRM; hSNF2a; MGC74511; Possible global transcription activator SNF2L2; Probable global transcription activator SNF2L2; Protein brahma homolog; SMCA2; SNF2 alpha; SNF2 like 2; SNF2/SWI2 like protein 2; SNF2-alpha; SNF2LA; Sth1p; Sucrose nonfermenting 2 like protein 2; SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily A member 2; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2

Clonality

Monoclonal, Recombinant

Clone

A624

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Epigenetics and Nuclear Signaling

Purification

Protein A purified

Concentration

1 mg/mL

Dilution

WB 1:1000; IHC 1:500-1:3000

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Shipping Conditions

Ice bag

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

181 kDa

Observed Molecular Weight

220 kDa

Isotype

IgG, κ