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Product details

Recombinant IL-1RA Monoclonal Antibody

Catalog number AN301912L-01

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Price for AN301912L-01

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Size / count 50 µL

Specifications

Catalog number
AN301912L-01
Size / count
50 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
The founding members of the interleukin-1 (IL-1) superfamily include pro-inflammatory cytokines IL-1α, IL-1β and IL-1 receptor antagonist (IL-1RA) . At least six similar proteins have been recently identified, including a homolog of IL-1RA (IL1F5) . IL-1a, IL-1b and IL-1RA are mainly expressed in macrophages, monocytes, and dendritic cells. IL-1RA acts as an anti-inflammatory cytokine, binding the IL-1 receptor to limit the response to inflammation. Because it plays a key role in regulating the inflammatory response, recombinant IL-1RA is a therapeutic agent used in the treatment of diseases such as rheumatoid arthritis. Alternatively, mutation of the corresponding IL-1RA gene may be associated with susceptibility to the development of specific cancers.
Abbreviation
IL-1RA
UniProt
P18510
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Recombinant human IL-1RA fragment
Target
IL1F; MVCD; IL1RN; DIRA; ICIL-1RA; IL-1RN; IL-1ra; IL-1ra3; IL1F3; IL1RA; IRAP; MVCD4; Anakinra; IL1 inhibitor; Interleukin-1 receptor antagonist protein; F630041P17Rik; ICIL 1RA; ICIL1RA; IL1RN (IL1F3) ; Interleukin 1 receptor antagonist; Intracellular IL 1 receptor antagonist type II; Intracellular interleukin 1 receptor antagonist (icIL 1ra) ; MGC10430; Type II interleukin 1 receptor antagonist
Clonality
Monoclonal, Recombinant
Clone
A628
Conjugation
Unconjugated
Applications
WB; IHC; IF
Field of Research
Immunology
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:1000-1:2000; IHC 1:50-1:200; IF 1:50-1:100
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
20 kDa
Observed Molecular Weight
22 kDa
Isotype
IgG, κ

Frequently Asked Questions

What is the catalog number for Recombinant IL-1RA Monoclonal Antibody?

The catalog number for Recombinant IL-1RA Monoclonal Antibody is AN301912L.

What sizes are available for Recombinant IL-1RA Monoclonal Antibody?

Recombinant IL-1RA Monoclonal Antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does Recombinant IL-1RA Monoclonal Antibody come in?

Recombinant IL-1RA Monoclonal Antibody is available in 2 different pack sizes.

Is Recombinant IL-1RA Monoclonal Antibody in stock?

Recombinant IL-1RA Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant IL-1RA Monoclonal Antibody?

Recombinant IL-1RA Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Recombinant IL-1RA Monoclonal Antibody?

Estimated delivery time for Recombinant IL-1RA Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant IL-1RA Monoclonal Antibody?

The safety data sheet for Recombinant IL-1RA Monoclonal Antibody is available here: https://789.bio/eb/dbG4CS58.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

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