Recombinant Caveolin-3 Monoclonal Antibody

Catalog number AN301915L-01

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Price for AN301915L-01

Size / count 50 µL

Specifications

Catalog number: AN301915L-01
Size / count: 50 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: The 21-24 kDa integral proteins, caveolins, are the principal structural components of the cholesterol/sphingolipid-enriched plasma membrane microdomain caveolae. Three members of the caveolin family (caveolin-1, -2, and -3) have been identified with different tissue distributions. Caveolins form hetero- and homo-oligomers that interact with cholesterol and other lipids. Caveolins are involved in diverse biological functions, including vesicular trafficking, cholesterol homeostasis, cell adhesion, and apoptosis, and are also implicated in neurodegenerative disease. Caveolins interact with multiple signaling molecules, such as Gα subunit, tyrosine kinase receptors, PKCs, Src family tyrosine kinases, and eNOS. It is believed that caveolins serve as scaffolding proteins for the integration of signal transduction. Phosphorylation at Tyr14 is essential for caveolin association with SH2 or PTB domain-containing adaptor proteins, such as GRB7. Phosphorylation at Ser80 regulates caveolin binding to the ER membrane and entry into the secretory pathway.
Abbreviation: Caveolin-3
UniProt: P56539
Host: Rabbit
Reactivity: Human; Rat; Mouse
Immunogen: Recombinant human Caveolin-3 fragment
Target: LQT; CAV; VIP; CAV3; LGMD1C; LQT9; VIP-21; VIP21; Caveolin 3; Caveolin-3; M-caveolin; MGC126100; MGC126101; MGC126129; OTTHUMP00000115603; OTTHUMP00000207105; VIP 21
Clonality: Monoclonal, Recombinant
Clone: A631
Conjugation: Unconjugated
Applications: WB; IHC
Field of Research: Signal Transduction; Tags & Cell Markers; Cardiovascular; Developmental Biology
Purification: Protein A purified
Concentration: 1 mg/mL
Dilution: WB 1:1000; IHC 1:100-1:400
Buffer: PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions: Ice bag
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 17 kDa
Observed Molecular Weight: 17 kDa
Isotype: IgG, κ

Frequently Asked Questions

What is the catalog number for Recombinant Caveolin-3 Monoclonal Antibody?

The catalog number for Recombinant Caveolin-3 Monoclonal Antibody is AN301915L.

What sizes are available for Recombinant Caveolin-3 Monoclonal Antibody?

Recombinant Caveolin-3 Monoclonal Antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does Recombinant Caveolin-3 Monoclonal Antibody come in?

Recombinant Caveolin-3 Monoclonal Antibody is available in 2 different pack sizes.

Is Recombinant Caveolin-3 Monoclonal Antibody in stock?

Recombinant Caveolin-3 Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant Caveolin-3 Monoclonal Antibody?

Recombinant Caveolin-3 Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Recombinant Caveolin-3 Monoclonal Antibody?

Estimated delivery time for Recombinant Caveolin-3 Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant Caveolin-3 Monoclonal Antibody?

The safety data sheet for Recombinant Caveolin-3 Monoclonal Antibody is available here: https://789.bio/eb/FMDlqsoM.

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.