Recombinant DDB2 Monoclonal Antibody — image 1 of 2

Product details

Recombinant DDB2 Monoclonal Antibody

Catalog number AN301920L-01

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Price for AN301920L-01

Size / count 50 µL

Specifications

Catalog number: AN301920L-01
Size / count: 50 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Damaged DNA-Binding Protein (DDB) consists of a 127 kDa subunit (DDB-1) and a 48 kDa subunit (DDB-2) that contribute to the formation of the UV-damaged DNA-binding protein complex (UV-DDB) . In conjunction with CUL4A and ROC-1, the UV-DDB complex forms an E3 ubiquitin ligase that recognizes a broad spectrum of DNA lesions such as cyclobutane pyrimidine dimers, 6-4 photoproducts, apurinic sites and short mismatches. The complex polyubiquitinates components of the nucleotide excision repair pathway. Loss of DDB activity has been identified in a subset of xeroderma pigmentosum complementation group E (XP-E) patients and has been linked to the deficient repair of cyclobutane pyrimidine dimers in cells derived from these patients.
Abbreviation: DDB2
UniProt: Q92466
Host: Rabbit
Reactivity: Human
Immunogen: Recombinant human DDB2 fragment
Target: DDB; UV-DDB; DDB2; DDBB; UV-DDB2; XPE
Clonality: Monoclonal, Recombinant
Clone: A636
Conjugation: Unconjugated
Applications: WB; IHC
Field of Research: Epigenetics and Nuclear Signaling; Cancer
Purification: Protein A purified
Concentration: 1 mg/mL
Dilution: WB 1:1000; IHC 1:500-1:1000
Buffer: PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions: Ice bag
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 48 kDa
Observed Molecular Weight: 48 kDa
Isotype: IgG, κ

Frequently Asked Questions

What is the catalog number for Recombinant DDB2 Monoclonal Antibody?

The catalog number for Recombinant DDB2 Monoclonal Antibody is AN301920L.

What sizes are available for Recombinant DDB2 Monoclonal Antibody?

Recombinant DDB2 Monoclonal Antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does Recombinant DDB2 Monoclonal Antibody come in?

Recombinant DDB2 Monoclonal Antibody is available in 2 different pack sizes.

Is Recombinant DDB2 Monoclonal Antibody in stock?

Recombinant DDB2 Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant DDB2 Monoclonal Antibody?

Recombinant DDB2 Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Recombinant DDB2 Monoclonal Antibody?

Estimated delivery time for Recombinant DDB2 Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant DDB2 Monoclonal Antibody?

The safety data sheet for Recombinant DDB2 Monoclonal Antibody is available here: https://789.bio/eb/EvVCDuPg.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.