Recombinant GABA B Receptor 1 Monoclonal Antibody

Catalog number AN301934L-01

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Price for AN301934L-01

Size / count 50 µL

Specifications

Catalog number: AN301934L-01
Size / count: 50 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: GABA (γ-aminobutyric acid) is the primary inhibitory neurotransmitter in the central nervous system and interacts with three different receptors: GABA (A), GABA (B) and GABA (C) receptor. The metabotropic GABA (B) receptor is coupled to G proteins that modulate slow inhibitory synaptic transmission. Functional GABA (B) receptors form heterodimers of GABA (B) R1 and GABA (B) R2 where GABA (B) R1 binds the ligand and GABA (B) R2 is the primary G protein contact site. GABA (B) R1 has two isoforms: GABA (B) R1a and GABA (B) R1b. GABA (B) R1a is a 130 kD protein and GABA (B) R1b is a 95 kD protein. G proteins subsequently inhibit adenyl cylase activity and modulate inositol phospholipid hydrolysis. GABA (B) receptors have both pre- and postsynaptic inhibitions: presynaptic GABA (B) receptors inhibit neurotransmitter release through suppression of high threshold calcium channels, while postsynaptic GABA (B) receptors inhibit through coupled activation of inwardly rectifying potassium channels. In addition to synaptic inhibition, GABA (B) receptors may also be involved in hippocampal long-term potentiation, slow wave sleep and muscle relaxation.
Abbreviation: GABA B Receptor 1
UniProt: Q9UBS5
Host: Rabbit
Reactivity: Rat; Mouse
Immunogen: Recombinant human GABA B Receptor 1 fragment
Target: GABBR; GABABR; GABBR1; GABABR1; GABBR1-3; GB1; GPRC3A
Clonality: Monoclonal, Recombinant
Clone: A650
Conjugation: Unconjugated
Applications: WB; IHC
Field of Research: Neuroscience
Purification: Protein A purified
Concentration: 1 mg/mL
Dilution: WB 1:1000; IHC 1:200-1000
Buffer: PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions: Ice bag
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 108 kDa
Observed Molecular Weight: 108 kDa
Isotype: IgG, κ

Frequently Asked Questions

What is the catalog number for Recombinant GABA B Receptor 1 Monoclonal Antibody?

The catalog number for Recombinant GABA B Receptor 1 Monoclonal Antibody is AN301934L.

What sizes are available for Recombinant GABA B Receptor 1 Monoclonal Antibody?

Recombinant GABA B Receptor 1 Monoclonal Antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does Recombinant GABA B Receptor 1 Monoclonal Antibody come in?

Recombinant GABA B Receptor 1 Monoclonal Antibody is available in 2 different pack sizes.

Is Recombinant GABA B Receptor 1 Monoclonal Antibody in stock?

Recombinant GABA B Receptor 1 Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant GABA B Receptor 1 Monoclonal Antibody?

Recombinant GABA B Receptor 1 Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Recombinant GABA B Receptor 1 Monoclonal Antibody?

Estimated delivery time for Recombinant GABA B Receptor 1 Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant GABA B Receptor 1 Monoclonal Antibody?

The safety data sheet for Recombinant GABA B Receptor 1 Monoclonal Antibody is available here: https://789.bio/eb/e08x0xSI.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.