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Product details

Recombinant SLC25A12 Monoclonal Antibody

Catalog number AN301939L-01

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Price for AN301939L-01

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Size / count 50 µL

Specifications

Catalog number
AN301939L-01
Size / count
50 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
The calcium-binding mitochondrial carrier protein (SLC25A12), also named as ARALAR or AGC1, is an aspartate-glutamate exchange protein responsible for transporting mitochondrial aspartate across the mitochondrial inner membrane in exchange for cytosolic glutamate. SLC25A12 and other proteins of the aspartate-glutamate carrier (AGC) group are required for the transfer of mitochondrial aspartate to the cytosol, a key step in urea synthesis. Research studies using SLC25A12-knockout mice indicate that SLC25A12 plays an important role in proper CNS myelination. Mice lacking SLC25A12 suffer from hypomyelination as a result of a lack of oligodendrocyte maturation caused by decreased brain N-acetylaspartate levels. Mutation of the corresponding SLC25A12 gene can result in global cerebral hypomyelination and severe psychomotor retardation, caused by deficient SLC25A12 activity and limited mitochondrial aspartate efflux.
Abbreviation
SLC25A12
UniProt
O75746
Host
Rabbit
Reactivity
Human; Rat; Mouse
Immunogen
Recombinant human SLC25A12 fragment
Target
AGC; EIEE; SLC25A; SLC25A12; AGC1; ARALAR; EIEE39; ARALAR1; Araceli hiperlarga; Calcium binding mitochondrial carrier superfamily member; Calcium binding mitochondrial carrier superfamily member Aralar1; Calcium-binding mitochondrial carrier protein Aralar1; CMC1; member 12; Mitochondrial aspartate glutamate carrier 1; solute carrier family 25; Solute carrier family 25 (aspartate/glutamate carrier) member 12; Solute carrier family 25 (mitochondrial carrier Aralar) member 12; Solute carrier family 25 member 12
Clonality
Monoclonal, Recombinant
Clone
A655
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Neuroscience; Tags & Cell Markers; Signal Transduction; Metabolism
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:2000-1:5000; IHC 1:50-1:100
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
75 kDa
Observed Molecular Weight
75 kDa
Isotype
IgG, κ

Frequently Asked Questions

What is the catalog number for Recombinant SLC25A12 Monoclonal Antibody?

The catalog number for Recombinant SLC25A12 Monoclonal Antibody is AN301939L.

What sizes are available for Recombinant SLC25A12 Monoclonal Antibody?

Recombinant SLC25A12 Monoclonal Antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does Recombinant SLC25A12 Monoclonal Antibody come in?

Recombinant SLC25A12 Monoclonal Antibody is available in 2 different pack sizes.

Is Recombinant SLC25A12 Monoclonal Antibody in stock?

Recombinant SLC25A12 Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant SLC25A12 Monoclonal Antibody?

Recombinant SLC25A12 Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Recombinant SLC25A12 Monoclonal Antibody?

Estimated delivery time for Recombinant SLC25A12 Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant SLC25A12 Monoclonal Antibody?

The safety data sheet for Recombinant SLC25A12 Monoclonal Antibody is available here: https://789.bio/eb/1AhDQ6Xe.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

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