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Product details

Recombinant eIF4G1 Monoclonal Antibody

Catalog number AN301953L-01

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Price for AN301953L-01

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Size / count 50 µL

Specifications

Catalog number
AN301953L-01
Size / count
50 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
The initiation of translation is an important biological event and a variety of factors contribute to this process. Members of the eIF4 translation initiation factor family bind to the 5' m7GTP mRNA cap and unwind the mRNA secondary structure. The amino-terminal portion of eIF4G physically associates with eIF4E to stimulate the binding of eIF4E to the mRNA cap structure. eIF4G also interacts with eIF3 and eIF4A and serves as an adaptor molecule in the eIF4 complex. Moreover, eIF4G plays a role in internal ribosomal entry site (IRES) -mediated initiation of translation. The eIF4G family includes eIF4G1 (eIF4GI), eIF4G2 (p97, DAP5 or NAT1), and eIF4G3 (eIF4GII) . These factors share a homologous sequence that provides for interaction with initiation factors eIF3 and eIF4A. Both eIF4G1 and eIF4G3 are involved in cap-dependent translation, while eIF4G2 plays a role in IRES-mediated translation of some genes during cell stress.
Abbreviation
EIF4G1
UniProt
Q04637
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Recombinant human eIF4G1 fragment
Target
PARK; DKFZp686A; eIF 4 gamma; eIF-4-gamma; Eukaryotic translation initiation factor 4 gamma; IF4G; EIF4G1; EIF-4G1; EIF4F; EIF4G; EIF4GI; P220; PARK18; DKFZp686A1451; eIF 4 gamma 1; eIF 4G 1; eIF 4G1; EIF4 gamma; eIF-4G 1; eIF-4-gamma 1; Eukaryotic translation initiation factor 4 gamma 1; IF4G1
Clonality
Monoclonal, Recombinant
Clone
A669
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Epigenetics and Nuclear Signaling
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:1000; IHC 1:500-1:1000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
175 kDa
Observed Molecular Weight
250 kDa
Isotype
IgG, κ

Frequently Asked Questions

What is the catalog number for Recombinant eIF4G1 Monoclonal Antibody?

The catalog number for Recombinant eIF4G1 Monoclonal Antibody is AN301953L.

What sizes are available for Recombinant eIF4G1 Monoclonal Antibody?

Recombinant eIF4G1 Monoclonal Antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does Recombinant eIF4G1 Monoclonal Antibody come in?

Recombinant eIF4G1 Monoclonal Antibody is available in 2 different pack sizes.

Is Recombinant eIF4G1 Monoclonal Antibody in stock?

Recombinant eIF4G1 Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant eIF4G1 Monoclonal Antibody?

Recombinant eIF4G1 Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Recombinant eIF4G1 Monoclonal Antibody?

Estimated delivery time for Recombinant eIF4G1 Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant eIF4G1 Monoclonal Antibody?

The safety data sheet for Recombinant eIF4G1 Monoclonal Antibody is available here: https://789.bio/eb/DEECFhjh.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

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