Recombinant SP1 Monoclonal Antibody — image 1 of 4

Product details

Recombinant SP1 Monoclonal Antibody

Catalog number AN301966L-01

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Price for AN301966L-01

Size / count 50 µL

Specifications

Catalog number: AN301966L-01
Size / count: 50 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Specificity protein 1 (SP1) is a ubiquitously expressed transcription factor belonging to the family of C2H2-type zinc finger containing DNA-binding proteins. SP1 binds GC-rich motifs with high affinity and regulates the expression of numerous mammalian genes. It interacts with many other transcription factors, such as c-Myc, EGR1, and Stat1, and with basal transcription machinery components. SP1 interacts with chromatin-modifying factors, such as histone deacetylases (HDACs) and p300 in chromatin remodeling. Transcriptional activity and stability of SP1 are regulated by post-translational modification, including phosphorylation, acetylation, ubiquitination, and glycosylation. Glycosylation of SP1 following insulin treatment leads to increased nuclear localization, while glucagon treatment increases cytoplasmic SP1 levels. Investigators have found high levels of SP1 in patients with Alzheimer's disease.
Abbreviation: SP1
UniProt: P08047
Host: Rabbit
Reactivity: Human; Rat; Mouse
Immunogen: Recombinant human SP1 fragment
Target: Specificity protein; Transcription factor Sp; SP1; SP 1; Sp1 transcription factor; Specificity protein 1; Transcription factor Sp1; TSFP 1; TSFP1
Clonality: Monoclonal, Recombinant
Clone: A682
Conjugation: Unconjugated
Applications: WB; IHC
Field of Research: Epigenetics and Nuclear Signaling; Stem Cells; Metabolism
Purification: Protein A purified
Concentration: 1 mg/mL
Dilution: WB 1:1000; IHC 1:50
Buffer: PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions: Ice bag
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 81 kDa
Observed Molecular Weight: 100 kDa
Isotype: IgG, κ

Frequently Asked Questions

What is the catalog number for Recombinant SP1 Monoclonal Antibody?

The catalog number for Recombinant SP1 Monoclonal Antibody is AN301966L.

What sizes are available for Recombinant SP1 Monoclonal Antibody?

Recombinant SP1 Monoclonal Antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does Recombinant SP1 Monoclonal Antibody come in?

Recombinant SP1 Monoclonal Antibody is available in 2 different pack sizes.

Is Recombinant SP1 Monoclonal Antibody in stock?

Recombinant SP1 Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant SP1 Monoclonal Antibody?

Recombinant SP1 Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Recombinant SP1 Monoclonal Antibody?

Estimated delivery time for Recombinant SP1 Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant SP1 Monoclonal Antibody?

The safety data sheet for Recombinant SP1 Monoclonal Antibody is available here: https://789.bio/eb/6Cz0aRgi.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.