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Product details

Recombinant CD8 beta Monoclonal Antibody

Catalog number AN301982L-01

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Price for AN301982L-01

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Size / count 50 µL

Specifications

Catalog number
AN301982L-01
Size / count
50 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
Cluster of Differentiation 8 (CD8) is a disulphide-linked heterodimer consisting of the unrelated α and β subunits. Each subunit is a glycoprotein composed of a single extracellular Ig-like domain, a polypeptide linker, a transmembrane part and a short cytoplasmic tail. On T cells, CD8 is the coreceptor for the T cell receptor (TCR), and these two distinct structures recognize the Antigen–Major Histocompatibility Complex (MHC) . Specifically, the Ig-like domain of CD8α interacts with the α3-domain of the MHC class I molecule. CD8 ensures specificity of the TCR–antigen interaction, prolongs the contact between the T cell and the antigen presenting cell, and the α chain recruits the tyrosine kinase Lck, which is essential for T cell activation.
Abbreviation
CD8 beta
UniProt
P10966
Host
Rabbit
Reactivity
Mouse
Immunogen
Peptide. This information is proprietary to PTMab.
Target
LYT; LEU; CD8B; CD8B1; LEU2; LY3; LYT3; P37; T-Cell Surface Glycoprotein CD8 Beta Chain; CD8; Lyt3
Clonality
Monoclonal, Recombinant
Clone
A702
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Immunology
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:1000; IHC 1:100
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
24 kDa
Observed Molecular Weight
28-32 kDa
Isotype
IgG, κ

Frequently Asked Questions

What is the catalog number for Recombinant CD8 beta Monoclonal Antibody?

The catalog number for Recombinant CD8 beta Monoclonal Antibody is AN301982L.

What sizes are available for Recombinant CD8 beta Monoclonal Antibody?

Recombinant CD8 beta Monoclonal Antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does Recombinant CD8 beta Monoclonal Antibody come in?

Recombinant CD8 beta Monoclonal Antibody is available in 2 different pack sizes.

Is Recombinant CD8 beta Monoclonal Antibody in stock?

Recombinant CD8 beta Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant CD8 beta Monoclonal Antibody?

Recombinant CD8 beta Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Recombinant CD8 beta Monoclonal Antibody?

Estimated delivery time for Recombinant CD8 beta Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant CD8 beta Monoclonal Antibody?

The safety data sheet for Recombinant CD8 beta Monoclonal Antibody is available here: https://789.bio/eb/QO82WcmN.

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

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