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Product details

Recombinant EAAT3 Monoclonal Antibody

Catalog number AN302009L-01

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Price for AN302009L-01

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Size / count 50 µL

Specifications

Catalog number
AN302009L-01
Size / count
50 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
During neurotransmission, glutamate is released from vesicles of the presynaptic cell, and glutamate receptors (e.g., NMDA Receptor, AMPA Receptor) bind glutamate for activation at the opposing postsynaptic cell. Excitatory amino acid transporters (EAATs) regulate and maintain extracellular glutamate concentrations below excitotoxic levels. In addition, glutamate transporters may limit the duration of synaptic excitation by an electrogenic process in which the transmitter is cotransported with three sodium ions and one proton, followed by countertransport of a potassium ion. Five EAATs (EAAT1-5) have been identified. EAAT1 and EAAT2 are expressed mainly in glia, while EAAT3, EAAT4, and EAAT5 are considered to be neuronal transporters. EAAT3 is found in the perisynaptic areas and cell bodies of glutamatergic and GABAergic neurons. Research studies have implicated abnormal EAAT3 expression in the pathophysiology of Schizophrenia.
Abbreviation
EAAT3
UniProt
P43005
Host
Rabbit
Reactivity
Human
Immunogen
Peptide. This information is proprietary to PTMab.
Target
EAAC; EAAT; SCZD; SLC1A; SLC1A1; DCBXA; EAAC1; EAAT3; SCZD18; EAA3; EAAC 1; EAAT 3; Excitatory amino acid carrier 1; Excitatory amino acid carrier1; Excitatory amino acid transporter 3; Excitatory amino acid transporter3; Excitatory amino-acid carrier 1; GLUTAMATE TRANSPORTER; HIGH-AFFINITY; MEAAC 1; MEAAC1; member 1; Neuronal and epithelial glutamate transporter; REAAC 1; REAAC1; Slc1 a1; Slc1a 1; Sodium dependent glutamate/aspartate transporter 3; Sodium-dependent glutamate/aspartate transporter 3; Solute carrier family 1; Solute carrier family 1 (neuronal / epithelial high affinity glutamate transporter; Solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter; SOLUTE CARRIER FAMILY 1 (NEURONAL/EPITHELIAL HIGH AFFINITY GLUTAMATE TRANSPORTER) ; Solute carrier family 1 member 1; system Xag)
Clonality
Monoclonal, Recombinant
Clone
A729
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Neuroscience
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:1000; IHC 1:500-1:1000
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
57 kDa
Observed Molecular Weight
70 kDa
Isotype
IgG, κ

Frequently Asked Questions

What is the catalog number for Recombinant EAAT3 Monoclonal Antibody?

The catalog number for Recombinant EAAT3 Monoclonal Antibody is AN302009L.

What sizes are available for Recombinant EAAT3 Monoclonal Antibody?

Recombinant EAAT3 Monoclonal Antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does Recombinant EAAT3 Monoclonal Antibody come in?

Recombinant EAAT3 Monoclonal Antibody is available in 2 different pack sizes.

Is Recombinant EAAT3 Monoclonal Antibody in stock?

Recombinant EAAT3 Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant EAAT3 Monoclonal Antibody?

Recombinant EAAT3 Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Recombinant EAAT3 Monoclonal Antibody?

Estimated delivery time for Recombinant EAAT3 Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant EAAT3 Monoclonal Antibody?

The safety data sheet for Recombinant EAAT3 Monoclonal Antibody is available here: https://789.bio/eb/a8y3ySIh.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.

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