Recombinant Histone H3.3 Monoclonal Antibody — image 1 of 4

Product details

Recombinant Histone H3.3 Monoclonal Antibody

Catalog number AN302024L-01

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Price for AN302024L-01

Size / count 50 µL

Specifications

Catalog number: AN302024L-01
Size / count: 50 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Histone H3.3 is a histone H3 variant that replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Abbreviation: Histone H3.3
UniProt: P84243
Host: Rabbit
Reactivity: Human; Rat; Mouse
Immunogen: Peptide. This information is proprietary to PTMab.
Target: H3F; histone H; H3F3A; H3.3A; H3F3; histone H3.3; family 3B (H3.3B) ; H3 histone; H3 histone family 3A; H3 histone family 3B; H3.3; H33; Histone H3.3Q; Histone H3.A; Histone H3.B; MGC87782; MGC87783; H3.3B; H3F3B; H3-3A; H3-3B; PP781
Clonality: Monoclonal, Recombinant
Clone: A744
Conjugation: Unconjugated
Applications: WB; IHC
Field of Research: Epigenetics and Nuclear Signaling
Purification: Protein A purified
Concentration: 1 mg/mL
Dilution: WB 1:1000; IHC 1:500-1:1000
Buffer: PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions: Ice bag
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 15 kDa
Observed Molecular Weight: 15 kDa
Isotype: IgG, κ

Frequently Asked Questions

What is the catalog number for Recombinant Histone H3.3 Monoclonal Antibody?

The catalog number for Recombinant Histone H3.3 Monoclonal Antibody is AN302024L.

What sizes are available for Recombinant Histone H3.3 Monoclonal Antibody?

Recombinant Histone H3.3 Monoclonal Antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does Recombinant Histone H3.3 Monoclonal Antibody come in?

Recombinant Histone H3.3 Monoclonal Antibody is available in 2 different pack sizes.

Is Recombinant Histone H3.3 Monoclonal Antibody in stock?

Recombinant Histone H3.3 Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant Histone H3.3 Monoclonal Antibody?

Recombinant Histone H3.3 Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Recombinant Histone H3.3 Monoclonal Antibody?

Estimated delivery time for Recombinant Histone H3.3 Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant Histone H3.3 Monoclonal Antibody?

The safety data sheet for Recombinant Histone H3.3 Monoclonal Antibody is available here: https://789.bio/eb/302fw6Sa.

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.