Recombinant AID Monoclonal Antibody

Catalog number AN302047L-01

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Price for AN302047L-01

Size / count 50 µL

Specifications

Catalog number: AN302047L-01
Size / count: 50 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Activation-induced cytidine deaminase (AID) is thought to modify RNA due to its high homology to the RNA editing enzyme APOBEC-1. This function, however, has not been confirmed in in vitro studies, which show that AID has significant cytidine deaminase activity, and that this activity is blocked by zinc chelation.The B cell immune system must specifically recognize several infectious agents, which vastly outnumber immunoglobulin gene segments present in a given organism. Mechanisms such as somatic hypermutation, isotype switch recombination and gene conversion introduce diversity and specificity to the immune system. Analysis of mouse models and patients with AID deficiency has established a link between all three of these mechanisms and AID function. AID protein is detected in germinal center centroblast and germinal center derived lymphomas (Burkitt lymphoma), but not in pre-germinal center B cells or post-germinal center neoplasms (B cell chronic lymphocytic leukemia and multiple myeloma) .
Abbreviation: AID
UniProt: Q9GZX7
Host: Rabbit
Reactivity: Human
Immunogen: Peptide. This information is proprietary to PTMab.
Target: AID; AICDA
Clonality: Monoclonal, Recombinant
Clone: A767
Conjugation: Unconjugated
Applications: WB; IHC
Field of Research: Immunology; Epigenetics and Nuclear Signaling
Purification: Protein A purified
Concentration: 1 mg/mL
Dilution: WB 1:1000; IHC 1:2000
Buffer: PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions: Ice bag
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 24 kDa
Observed Molecular Weight: 23 kDa
Isotype: IgG, κ

Frequently Asked Questions

What is the catalog number for Recombinant AID Monoclonal Antibody?

The catalog number for Recombinant AID Monoclonal Antibody is AN302047L.

What sizes are available for Recombinant AID Monoclonal Antibody?

Recombinant AID Monoclonal Antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does Recombinant AID Monoclonal Antibody come in?

Recombinant AID Monoclonal Antibody is available in 2 different pack sizes.

Is Recombinant AID Monoclonal Antibody in stock?

Recombinant AID Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant AID Monoclonal Antibody?

Recombinant AID Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Recombinant AID Monoclonal Antibody?

Estimated delivery time for Recombinant AID Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant AID Monoclonal Antibody?

The safety data sheet for Recombinant AID Monoclonal Antibody is available here: https://789.bio/eb/reMuqkz1.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.