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Product details

Recombinant ATP Citrate Lyase Monoclonal Antibody

Catalog number AN302052L-01

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Price for AN302052L-01

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Size / count 50 µL

Specifications

Catalog number
AN302052L-01
Size / count
50 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
ATP-citrate lyase (ACL) is a homotetramer that catalyzes the formation of acetyl-CoA and oxaloacetate (OAA) in the cytosol, which is the keystep for the biosynthesis of fatty acids, cholesterol and acetylcholine, as well as for glucogenesis. Nutrients and hormones regulate theexpression level and phosphorylation of ATP-citrate lyase. It is phosphorylated by GSK-3 on Thr446 and Ser450. Ser455 of ATP-citrate lyasehas been reported to be phosphorylated by PKA and Akt. Phosphorylation on Ser455 abolishes the homotropic allosteric regulation by citrateand enhances the catalytic activity of the enzyme.
Abbreviation
ATP Citrate Lyase
UniProt
P53396
Host
Rabbit
Reactivity
Human; Rat; Mouse
Immunogen
Peptide. This information is proprietary to PTMab.
Target
OTTHUMP; ACLY; ACL; ATPCL; CLATP; ATP citrate (pro-S) lyase; ATP citrate lyase; ATP citrate synthase; ATP-citrate (pro-S-) -lyase; ATPcitrate synthase; ATP-citrate synthase; Citrate cleavage enzyme; OTTHUMP00000164773
Clonality
Monoclonal, Recombinant
Clone
A772
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Signal Transduction; Cancer; Metabolism
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:1000; IHC 1:500
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
120 kDa
Observed Molecular Weight
125 kDa
Isotype
IgG, κ

Frequently Asked Questions

What is the catalog number for Recombinant ATP Citrate Lyase Monoclonal Antibody?

The catalog number for Recombinant ATP Citrate Lyase Monoclonal Antibody is AN302052L.

What sizes are available for Recombinant ATP Citrate Lyase Monoclonal Antibody?

Recombinant ATP Citrate Lyase Monoclonal Antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does Recombinant ATP Citrate Lyase Monoclonal Antibody come in?

Recombinant ATP Citrate Lyase Monoclonal Antibody is available in 2 different pack sizes.

Is Recombinant ATP Citrate Lyase Monoclonal Antibody in stock?

Recombinant ATP Citrate Lyase Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant ATP Citrate Lyase Monoclonal Antibody?

Recombinant ATP Citrate Lyase Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Recombinant ATP Citrate Lyase Monoclonal Antibody?

Estimated delivery time for Recombinant ATP Citrate Lyase Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant ATP Citrate Lyase Monoclonal Antibody?

The safety data sheet for Recombinant ATP Citrate Lyase Monoclonal Antibody is available here: https://789.bio/eb/oSoZqzWB.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

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