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Product details

Recombinant Phospho-HSP27 (Ser78) Monoclonal Antibody

Catalog number AN302087L-01

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Price for AN302087L-01

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Size / count 50 µL

Specifications

Catalog number
AN302087L-01
Size / count
50 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
Hsp27 is one of the small HSPs that are constitutively expressed at different levels in various cell types and tissues. Like other small HSPs, HSP27 is regulated at both the transcriptional and posttranslational levels. In response to stress, the HSP27 expression increases several-fold to confer cellular resistance to the adverse environmental change. HSP27 is phosphorylated at Ser15, Ser78, and Ser82 by MAPKAPK-2 as a result of the activation of the p38 MAP kinase pathway. Phosphorylation of HSP27 causes a change in its tertiary structure, which shifts from large homotypic multimers to dimers and monomers. It has been shown that phosphorylation and increased concentration of HSP27 modulates actin polymerization and reorganization.
Abbreviation
Phospho-HSP27 (Ser78)
UniProt
P04792
Host
Rabbit
Reactivity
Human
Immunogen
Phosphorylated human HSP27 (Ser78) peptide
Target
SRP; HSPB; HEL-S; HSP; HSPB1; CMT2F; HEL-S-102; HMN2B; HS.76067; HSP27; HSP28; Hsp25; SRP27;28 kDa heat shock protein; DKFZp586P1322; epididymis secretory protein Li 102; Estrogen regulated 24 kDa protein; Estrogen-regulated 24 kDa protein; Heat shock 25kDa protein 1; Heat shock 27 kDa protein; Heat shock 27kD protein 1; Heat shock 27kDa protein; Heat shock 27kDa protein 1; Heat shock 28kDa protein 1; Heat Shock Protein 27; Heat shock protein beta 1; Heat shock protein beta-1; heat shock protein family B (small) member 1; Hsp 25; HSP 27; Hsp 28; Hsp B1; Stress responsive protein 27; Stress-responsive protein 27
Clonality
Monoclonal, Recombinant
Clone
A811
Conjugation
Unconjugated
Applications
WB; IHC; IF; IP
Field of Research
Signal Transduction; Cancer; Cardiovascular
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
WB 1:500-1:1000; IHC 1:100-1:500; IF 1:50; IP 1:50-1:100
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
23 kDa
Observed Molecular Weight
27 kDa
Isotype
IgG, κ

Frequently Asked Questions

What is the catalog number for Recombinant Phospho-HSP27 (Ser78) Monoclonal Antibody?

The catalog number for Recombinant Phospho-HSP27 (Ser78) Monoclonal Antibody is AN302087L.

What sizes are available for Recombinant Phospho-HSP27 (Ser78) Monoclonal Antibody?

Recombinant Phospho-HSP27 (Ser78) Monoclonal Antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does Recombinant Phospho-HSP27 (Ser78) Monoclonal Antibody come in?

Recombinant Phospho-HSP27 (Ser78) Monoclonal Antibody is available in 2 different pack sizes.

Is Recombinant Phospho-HSP27 (Ser78) Monoclonal Antibody in stock?

Recombinant Phospho-HSP27 (Ser78) Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant Phospho-HSP27 (Ser78) Monoclonal Antibody?

Recombinant Phospho-HSP27 (Ser78) Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Recombinant Phospho-HSP27 (Ser78) Monoclonal Antibody?

Estimated delivery time for Recombinant Phospho-HSP27 (Ser78) Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant Phospho-HSP27 (Ser78) Monoclonal Antibody?

The safety data sheet for Recombinant Phospho-HSP27 (Ser78) Monoclonal Antibody is available here: https://789.bio/eb/NraUn214.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

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