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Product details

Recombinant Histone H3 (Di Methyl Lys14) Monoclonal Antibody

Catalog number AN302108L-01

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Price for AN302108L-01

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Size / count 50 µL

Specifications

Catalog number
AN302108L-01
Size / count
50 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
Histone post-translational modifications (PTMs) are key mechanisms of epigenetics that modulate chromatin structures, termed as “histone code”. The PTMs on histone including acetylation, methylation, phosphorylation and novel acylations directly affect the accessibility of chromatin to transcription factors and other epigenetic regulators, altering genome stability, gene transcription, etc. Histone methylation occurs primarily at lysine and arginine residues on the amino terminal of core histones. Methylation of histones can either increase or decrease transcription of genes, depending on which amino acids (Lys or Arg) in the histones are methylated and how many methyl groups are attached (mono-, di-, Trimethylation on Lys, mono-di-symmetric/asymmetric methylation on Arg) . Mostly, lysine methylation occurs primarily on histone H3 Lys4, 9, 27, 36, 79 and H4 Lys20, while Arginine methylation occurs primarily on histone H3 Arg2, 8, 17, 26 and H4 Arg3. histone methyltransferases (HMTs) and histone demethylases (HDMs) are major regulating factors.
Abbreviation
Histone H3 (Di Methyl Lys14)
UniProt
P68431
Host
Rabbit
Reactivity
Human; Rat; Mouse
Immunogen
Dimethylated human histone H3 (Lys14) peptide
Target
Histone H; H3C; H3/A; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3FA; H3C10; H3C11; H3C12; HIST1H3A; H3C1; Histone H3.1; Histone H3/a; Histone H3/b; H3FL; HIST1H3B; H3FC; HIST1H3C; H3FB; HIST1H3D; H3FD; HIST1H3E; H3FI; HIST1H3F; H3FH; HIST1H3G; H3FK; HIST1H3H; H3FF; HIST1H3I; H3FJ; HIST1H3J; H3/A; H3FA; H3FB; H3FC; H3FD; H3FF; H3FH; H3FI; H3FJ; H3FK; H3FL; Hist1h3a; HIST1H3B; HIST1H3C; HIST1H3D; HIST1H3E; HIST1H3F; HIST1H3G; HIST1H3H; HIST1H3I; HIST1H3J; Histone H3.1; Histone H3/a; Histone H3/b; H3 histone family; H31; H3a; histone 1; Histone cluster 1; Histone H3/c; Histone H3/d; Histone H3/f; Histone H3/h; Histone H3/i; Histone H3/j; Histone H3/k; Histone H3/l; member A
Clonality
Monoclonal, Recombinant
Clone
A832
Conjugation
Unconjugated
Applications
WB; IHC; IF; ChIP
Field of Research
Epigenetics and Nuclear Signaling; Isotype; Loading Controls
Purification
Protein A purified
Concentration
1 mg/mL
Dilution
6
Buffer
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
15 kDa
Observed Molecular Weight
15 kDa
Isotype
IgG, κ

Frequently Asked Questions

What is the catalog number for Recombinant Histone H3 (Di Methyl Lys14) Monoclonal Antibody?

The catalog number for Recombinant Histone H3 (Di Methyl Lys14) Monoclonal Antibody is AN302108L.

What sizes are available for Recombinant Histone H3 (Di Methyl Lys14) Monoclonal Antibody?

Recombinant Histone H3 (Di Methyl Lys14) Monoclonal Antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does Recombinant Histone H3 (Di Methyl Lys14) Monoclonal Antibody come in?

Recombinant Histone H3 (Di Methyl Lys14) Monoclonal Antibody is available in 2 different pack sizes.

Is Recombinant Histone H3 (Di Methyl Lys14) Monoclonal Antibody in stock?

Recombinant Histone H3 (Di Methyl Lys14) Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant Histone H3 (Di Methyl Lys14) Monoclonal Antibody?

Recombinant Histone H3 (Di Methyl Lys14) Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Recombinant Histone H3 (Di Methyl Lys14) Monoclonal Antibody?

Estimated delivery time for Recombinant Histone H3 (Di Methyl Lys14) Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant Histone H3 (Di Methyl Lys14) Monoclonal Antibody?

The safety data sheet for Recombinant Histone H3 (Di Methyl Lys14) Monoclonal Antibody is available here: https://789.bio/eb/Rc5OyqGl.

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

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