- Catalog number
- KC-6276-01
- Size / count
- 50 μL
- Dry ice
- No
- Hazardous
- No
- Discontinued
- No
- Gene Name
- AKT1/AKT2/AKT3
- Gene ID
- 207,208,10000
- UniProt
- P31749/P31751/Q9Y243
- Antigen Species
- Human
- Reactivity
- Human, Mouse, Rat
- Cross Reactivity
- Not tested
- Immunogen
- Purified recombinant human AKT1 protein fragments expressed in E.coli.AKT1 interacts (via the C-terminus) with CCDC88A (via its C-terminus) . Interacts with GRB10; the interaction leads to GRB10 phosphorylation thus promoting YWHAE-binding By similarity. Interacts with AGAP2 (isoform 2/PIKE-A) ; the interaction occurs in the presence of guanine nucleotides. Interacts with AKTIP. Interacts (via PH domain) with MTCP1, TCL1A AND TCL1B. Interacts with CDKN1B; the interaction phosphorylates CDKN1B promoting 14-3-3 binding and cell-cycle progression. Interacts with MAP3K5 and TRAF6. Interacts with BAD, PPP2R5B, STK3 and STK4. Interacts (via PH domain) with SIRT1. Interacts with SRPK2 in a phosphorylation-dependent manner. Interacts with RAF1. Interacts with TRIM13; the interaction ubiquitinates AKT1 leading to its proteasomal degradation. Interacts with TNK2 and CLK2. Interacts (via the C-terminus) with THEM4 (via its C-terminus) . Interacts with and phosphorylated by PDPK1.AKT2 interacts (via PH domain) with MTCP1, TCL1A AND TCL1B. Interacts with CLK2, PBH2 and TRAF6. AKT3 interacts (via PH domain) with TCL1A; this enhances AKT3 phosphorylation and activation. Interacts with TRAF6.
- Partner Proteins
- /
- Clone
- K01_2T10
- Conjugation
- Unconjugated
- Applications
- IP/ChIP&WB
- Validation
- IP/ChIP&WB
- Purity
- ≥85%
- Storage Temperature
- Avoid repeated freeze-thaw cycles. Upon receipt, * 1 month when stored at 2 to 8 °C * 12 months when aliquoted and stored at -20 °C or lower
- Recombinant Antibody
- Not recombinant
- WB Dilution
- 1:1000
- IP Dilution
- 1:20
- Formulation
- Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide, pH 7.3
- Antibody Type
- Monoclonal
- Gene Name Synonym
- /
- Target Alternative Name
- AKT1/AKT2/AKT3
- Host or Source
- Mouse
- Protein Name
- AKT serine/threonine kinase 1 etc.
- WB Description
- Succeed
- IHC description
- Fail (Lung Cancer)
- IP description
- Succeed
- Shipping Temperature
- Shipped at ambient temperature or with ice packs.
- Isotype
- IgG1