MLH1 Mouse Monoclonal Antibody [A9F7]

Catalog number HA601135

Price for HA601135

Size / count 100 µL

About this product

DNA mismatch repair protein Mlh1 or MutL protein homolog 1 is a protein that in humans is encoded by the MLH1 gene located on chromosome 3. It is a gene commonly associated with hereditary nonpolyposis colorectal cancer. Orthologs of human MLH1 have also been studied in other organisms including mouse and the budding yeast Saccharomyces cerevisiae. This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer. It is a human homolog of the E. coli DNA mismatch repair gene, mutL, which mediates protein-protein interactions during mismatch recognition, strand discrimination, and strand removal. Defects in MLH1 are associated with the microsatellite instability observed in hereditary nonpolyposis colon cancer. Alternatively spliced transcript variants encoding different isoforms have been described, but their full-length natures have not been determined.

Specifications

Catalog number: HA601135
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: COCA 2 antibody COCA2 antibody DNA mismatch repair protein Mlh1 antibody FCC 2 antibody FCC2 antibody hMLH 1 antibody hMLH1 antibody HNPCC 2 antibody HNPCC antibody HNPCC2 antibody MGC5172 antibody MLH 1 antibody MLH1 antibody MLH1_HUMAN antibody MutL homolog 1 (E. coli) antibody MutL homolog 1 antibody MutL homolog 1 colon cancer nonpolyposis type 2 antibody MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) antibody MutL protein homolog 1 antibody MutL, E. coli, homolog of, 1 antibody
Abbreviation: MLH1, COCA2
Swiss Prot: P40692 Human, Q9JK91 Mouse, P97679 Rat
Cellular Locus: Nucleus, Chromosome.
Host: Mouse
Species Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein within human MLH1 aa 452-751 / 751.
Isotype: IgG2b
Clone: A9F7
Conjugation: Non-conjugated
Type: Mouse monoclonal Antibody
Applications: WB, IHC-P
Positive Control: HeLa cell lysate, A549 cell lysate, HepG2 cell lysate, Jurkat cell lysate, NIH/3T3 cell lysate, F9 cell lysate, RAW264.7 cell lysate, C6 cell lysate, A431 cell lysate, Daudi cell lysate, K-562 cell lysate, HL-60 cell lysate, SW480 cell lysate, human colon carcinoma tissue, mouse colon tissue, rat small intestine tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000-1:2,000 ;IHC-P: 1:1,000
Purity: Protein A affinity purified.
Form: Liquid
Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 85 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for MLH1 Mouse Monoclonal Antibody [A9F7]?

The catalog number for MLH1 Mouse Monoclonal Antibody [A9F7] is HA601135.

What sizes are available for MLH1 Mouse Monoclonal Antibody [A9F7]?

MLH1 Mouse Monoclonal Antibody [A9F7] is available in the following size(s): 100 µL.

Is MLH1 Mouse Monoclonal Antibody [A9F7] in stock?

MLH1 Mouse Monoclonal Antibody [A9F7] is currently made to order / not held in immediate stock. Contact us for lead time.

What is MLH1 Mouse Monoclonal Antibody [A9F7] used for?

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.