Biotin Conjugated Human TRAIL Recombinant Rabbit Monoclonal Antibody [PSH08-06]

About this product

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues. This protein binds to several members of TNF receptor superfamily including TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and possibly also to TNFRSF11B/OPG. The activity of this protein may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and TNFRSF11B/OPG that cannot induce apoptosis. The binding of this protein to its receptors has been shown to trigger the activation of MAPK8/JNK, caspase 8, and caspase 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Specifications

Catalog number

HA722945B

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

Apo 2 ligand antibody APO 2L antibody Apo-2 ligand antibody Apo-2L antibody APO2L antibody CD253 antibody CD253 antigen antibody Chemokine tumor necrosis factor ligand superfamily member 10 antibody Protein TRAIL antibody TL2 antibody TNF Related Apoptosis Inducing Ligand antibody TNF related apoptosis inducing ligand TRAIL antibody TNF-related apoptosis-inducing ligand antibody TNF10_HUMAN antibody TNFSF10 antibody TRAIL antibody Tumor necrosis factor (ligand) family member 10 antibody Tumor Necrosis Factor (ligand) Superfamily Member 10 antibody Tumor necrosis factor apoptosis inducing ligand splice variant delta antibody Tumor necrosis factor ligand superfamily member 10 antibody

Abbreviation

Tumor necrosis factor ligand superfamily member 10 Apo-2 ligand (Apo-2L) TNF-related apoptosis-inducing ligand (Protein TRAIL) CD253 TNFSF10 APO2L, TRAIL

Swiss Prot

P50591 Human

Cellular Locus

Secreted.

Host

Rabbit

Species Reactivity

Human

Immunogen

Recombinant protein within Human TRAIL aa 114-281.

Isotype

IgG

Clone

PSH08-06

Conjugation

Biotin-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

ELISA (Det)

Positive Control

Recombinant Human TRAIL protein as the standard (HA210893).

Concentration

1 mg/mL

Dilution

ELISA (Det): Use at an assay dependent concentration. Can be paired for Sandwich ELISA with Rabbit monoclonal [PSH08-05] to Human TRAIL antibody (Capture) (HA722943) and recombinant Human TRAIL protein as the standard (HA210893). The reference range value is 16.5-4,000 pg/ml.

Purity

Protein A affinity purified.

Form

Liquid

Buffer

PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% ProClin300.

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes