LI Cadherin Recombinant Rabbit Monoclonal Antibody [JE60-34]

About this product

This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants. Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. LI-cadherin may have a role in the morphological organization of liver and intestine. Involved in intestinal peptide transport.

Specifications

Catalog number

HA721895

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

BILL-cadherin antibody CAD17_HUMAN antibody Cadherin 16 antibody Cadherin 16, formerly antibody Cadherin 17 antibody cadherin 17, LI cadherin (liver-intestine) antibody cadherin, liver-intestine antibody Cadherin-17 antibody CDH16 antibody CDH16, formerly antibody Cdh17 antibody FLJ26931 antibody Formerly Cadherin 16 antibody Formerly CDH16 antibody HPT 1 antibody HPT-1 cadherin antibody human intestinal peptide-associated transporter HPT-1 antibody human peptide transporter 1 antibody Intestinal peptide-associated transporter HPT 1 antibody Intestinal peptide-associated transporter HPT-1 antibody LI-cadherin antibody Liver Cadherin antibody liver intestine cadherin antibody Liver-intestine cadherin antibody

Abbreviation

Cadherin-17 Intestinal peptide-associated transporter HPT-1 Liver-intestine cadherin (LI-cadherin) CDH17

Swiss Prot

Q12864 Human

Cellular Locus

Cell membrane

Host

Rabbit

Species Reactivity

Human, Mouse

Immunogen

Recombinant protein within Human LI Cadherin aa 1-100 / 832.

Isotype

IgG

Clone

JE60-34

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IHC-P, IF-Tissue, IF-Cell, FC

Positive Control

Caco-2 cell lysate, LoVo cell lysate, Caco-2, human appendix tissue, human stomach tissue, mouse small intestine tissue.

Concentration

1 mg/mL

Dilution

WB: 1:1,000 ;IHC-P: 1:200-1:1,000 ;IF-Tissue: 1:100 ;IF-Cell: 1:100 ;FC: 1:1,000

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 92 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes