SESN2 / Sestrin-2 Recombinant Rabbit Monoclonal Antibody [PSH05-78]

Catalog number HA722489

Price for HA722489

Size / count 100 µL

About this product

Sestrin-2 also known as Hi95 is a protein that in humans is encoded by the SESN2 gene. This gene encodes a member of the sestrin family of PA26-related proteins. The encoded protein may function in the regulation of cell growth and survival. This protein may be involved in cellular response to different stress conditions. The Sestrins constitute a family of evolutionarily-conserved stress-inducible proteins that suppress oxidative stress and regulate adenosine monophosphate-dependent protein kinase (AMPK)-mammalian target of rapamycin (mTOR) signaling. By virtue of these activities, the Sestrins serve as important regulators of metabolic homeostasis. Accordingly, inactivation of Sestrin genes in invertebrates resulted in diverse metabolic pathologies, including oxidative damage, fat accumulation, mitochondrial dysfunction and muscle degeneration that resemble accelerated tissue aging.

Specifications

Catalog number: HA722489
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: DKFZp761M0212 antibody DKFZp761M02121 antibody Hi95 antibody Hypoxia induced gene 95 antibody MGC11758 antibody OTTHUMP00000003641 antibody OTTMUSP00000010184 antibody RP23 63D8.3 antibody SES2 antibody SESN 2 antibody SESN2 antibody SESN2_HUMAN antibody SEST2 antibody Sestrin 2 antibody Sestrin-2 antibody
Abbreviation: SESN2, Hi95, SEST2
Swiss Prot: P58004 Human, P58043 Mouse,
Cellular Locus: Cytoplasm.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide within human SESN2 aa 231-280.
Isotype: IgG
Clone: PSH05-78
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB
Positive Control: K-562 cell lysate, HEK-293 cell lysate, 293T cell lysate, HCT 116 cell lysate, LoVo cell lysate, HepG2 cell lysate, Jurkat cell lysate, U-87 MG cell lysate, NIH/3T3 cell lysate, RAW264.7 cell lysate, C6 cell lysate, PC-12 cell lysate.
Concentration: 1 mg/mL
Dilution: WB: 1:2,000
Purity: Protein A affinity purified.
Form: Liquid
Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 54 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for SESN2 / Sestrin-2 Recombinant Rabbit Monoclonal Antibody [PSH05-78]?

The catalog number for SESN2 / Sestrin-2 Recombinant Rabbit Monoclonal Antibody [PSH05-78] is HA722489.

What sizes are available for SESN2 / Sestrin-2 Recombinant Rabbit Monoclonal Antibody [PSH05-78]?

SESN2 / Sestrin-2 Recombinant Rabbit Monoclonal Antibody [PSH05-78] is available in the following size(s): 100 µL.

Is SESN2 / Sestrin-2 Recombinant Rabbit Monoclonal Antibody [PSH05-78] in stock?

SESN2 / Sestrin-2 Recombinant Rabbit Monoclonal Antibody [PSH05-78] is currently made to order / not held in immediate stock. Contact us for lead time.

What is SESN2 / Sestrin-2 Recombinant Rabbit Monoclonal Antibody [PSH05-78] used for?

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.