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Product details
Catalog number H12516033.25G
Price for H12516033.25G
Size / count 25 g
A very acid sensitive resin suitable for the synthesis of protected peptide fragments by the Fmoc strategy. In particular suitable for the preparation of C-terminal prolyl and cysteinyl peptides. Cleavage from this resin is achieved by using 1-95% TFA in DCM (containing 8% triisopropylsilane), AcOH/CF3OH/DCM, 0.5% TFA or hexafluoroisopropanol. Recently, this resin has been used in cyclization reactions under Heck reaction conditions, the solid phase synthesis of ß-peptides via the Arndt-Eistert homologation of Fmoc-protected amino acid diazoketones and in Mannich reactions of alkynes, secondary amines and aldehydes in the presence of a copper (I) salt leading to the corresponding aminomethyl alkynyl adducts.This resin can also be used in Fmoc peptide synthesis. Carboxylic acids can be released under very mild acidic conditions by treatment with AcOH/TFE/DCM or HFIP in DCM. Completely protected peptides are generated under these conditions. This resin is less sensitive towards acids compared to chlorotrityl resins. Coupling of the first amino acid is not carried out by activation, thus enantiomerization does not occur.
The catalog number for Chloro- (2'-chloro) trityl Polystyrene is H12516033.25G.
Chloro- (2'-chloro) trityl Polystyrene is available in the following size(s): 25 g.
Chloro- (2'-chloro) trityl Polystyrene is currently made to order / not held in immediate stock. Contact us for lead time.
A very acid sensitive resin suitable for the synthesis of protected peptide fragments by the Fmoc strategy. In particular suitable for the preparation of C-terminal prolyl and cysteinyl peptides. Cleavage from this resin is achieved by using 1-95% TFA in DCM (containing 8% triisopropylsilane), AcOH/
If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.
The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.
A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.
