- Home
- Shop
- New Categories
- New Blog
- Contact Us
- Cart
- Login
- Register
Select the image to view it full size.
Product details
Catalog number S30031.50G
Price for S30031.50G
Size / count 50 g
TentaGel® resins are grafted copolymers consisting of a low crosslinked polystyrene matrix on which polyethylene glycol (PEG or POE) is grafted via an ethyl ether group which increases stability towards acid treatment and minimizes PEG-leaching. The graft copolymer shows modified physicochemical properties which are highly dominated by the PEG moiety (and no longer by the polystyrene matrix) and has hydrophobic and hydrophilic properties. These copolymers are pressure stable and can be used in batch processes as well as under continuous flow conditions. The PEG spacer is in the range of MW 3000 Da. TentaGel® resins have high diffusion rates and excellent swelling in a wide range of solvents from e.g. toluene to water. This preactivated resin is ready for loading with nucleophilic compounds and amino acids under basic conditions. Due to the hygroscopic nature of TentaGel® resins, the resin should be used immediately. Standard resin for a large number of applications, useful in batch and flow through systems.This resin is recommended for synthesis of standard peptides up to 40 residues in length. This highly acid sensitive linker is useful for the immobilization of alcohols, amines and carboxylic acids. The sensitivity towards acids is very comparable to the 2-chlorotrityl linker. Cleavage is in general achieved by using either 5 - 50% TFA in DCM (containing 5% triisopropylsilane) or acetic acid. This resin can also be used in Fmoc peptide synthesis. Carboxylic acids can be released under very mild acidic conditions by treatment with AcOH/TFE/DCM or HFIP in DCM. Completely protected peptides are generated under these conditions. Residues which are sensitive to racemisation during esterification reactions like His and Cys can be attached to the resin without racemisation. Due to the bulkiness of the trityl group, diketopiperazine formation is suppressed which makes this linker ideal for peptides with C-terminal Pro.
The catalog number for TentaGel® S TRT-Cl is S30031.50G.
TentaGel® S TRT-Cl is available in the following size(s): 50 g.
TentaGel® S TRT-Cl is currently made to order / not held in immediate stock. Contact us for lead time.
TentaGel® resins are grafted copolymers consisting of a low crosslinked polystyrene matrix on which polyethylene glycol (PEG or POE) is grafted via an ethyl ether group which increases stability towards acid treatment and minimizes PEG-leaching. The graft copolymer shows modified physicochemical pro
Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.
Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.
If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.
