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Product details
Catalog number XV18130.031.25G
Price for XV18130.031.25G
Size / count 25 g
A Sophisticated Resin for the Solution of Synthesis Challenges. TentaGel® XV resin (XV stands for "Extended Swelling Volume") is a new member of the TentaGel® family. Modifications on the polystyrene backbone change the swelling properties of the PEG grafted resin. Swelling properties are in the same range or even higher compared to PEGA or Chematrix resins. The polar PEG spacers allow the composite resin to swell in a wide range of solvents including water, methanol, DMF, DCM. Nevertheless, the handling is still very easy and similar to other TentaGel® resins. The high swelling creates an extended reaction space. This enlarged reaction volume meets the requirement for ideal conditions for the synthesis of difficult sequences, aggregating peptides, mini proteins and PNAs in high purities and excellent yields. Purified yield of PNA4-peptide15-PNA11 Resin yield [%] Wang resin 0 Chematrix 20 TentaGel® XV 32 This preactivated resin is ready for loading with nucleophilic compounds and amino acids under basic conditions. Due to the hygroscopic nature of TentaGel® resins, the resin should be used immediately. This highly acid sensitive linker is useful for the immobilization of alcohols, amines and carboxylic acids. The sensitivity towards acids is very comparable to the 2-chlorotrityl linker. Cleavage is in general achieved by using either 5 - 50% TFA in DCM (containing 5% triisopropylsilane) or acetic acid. This resin can also be used in Fmoc peptide synthesis. Carboxylic acids can be released under very mild acidic conditions by treatment with AcOH/TFE/DCM or HFIP in DCM. Completely protected peptides are generated under these conditions. Residues which are sensitive to racemisation during esterification reactions like His and Cys can be attached to the resin without racemisation. Due to the bulkiness of the trityl group, diketopiperazine formation is suppressed which makes this linker ideal for peptides with C-terminal Pro.
The catalog number for TentaGel® XV TRT-Cl is XV18130.031.25G.
TentaGel® XV TRT-Cl is available in the following size(s): 25 g.
TentaGel® XV TRT-Cl is currently made to order / not held in immediate stock. Contact us for lead time.
A Sophisticated Resin for the Solution of Synthesis Challenges. TentaGel® XV resin (XV stands for "Extended Swelling Volume") is a new member of the TentaGel® family. Modifications on the polystyrene backbone change the swelling properties of the PEG grafted resin. Swelling properties are in the sam
Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.
If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.
The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.
